Fedrick J, Adelstein P
Br Med J. 1973 Dec 29;4(5895):753-6. doi: 10.1136/bmj.4.5895.753.
To assess the significance of the length of time between two pregnancies on the outcome of the second we used information collected by the British Perinatal Mortality Survey of 1958. From questionnaires on the 16,994 singleton births in the first week of March 1958 and the 7,117 singleton stillbirths and neonatal deaths in March, April, and May 1958 we abstracted information on the date and outcome of any preceding pregnancy. The interpregnancy interval was taken as the length of time between this preceding pregnancy and the last menstrual period before the index pregnancy. The most important factors influencing pregnancy spacing were outcome of the preceding delivery, social class, and maternal age. When these variables had been taken into account we found that the length of interpregnancy interval had little effect on stillbirth rates. High neonatal death rates, however, occurred when interpregnancy intervals were less than six months (P <0.005), though longer intervals had no significant effects.
为评估两次妊娠间隔时间对第二次妊娠结局的影响,我们采用了英国1958年围产期死亡率调查收集的信息。通过对1958年3月第一周的16994例单胎分娩问卷以及1958年3月、4月和5月的7117例单胎死产和新生儿死亡问卷,我们提取了前次妊娠的日期和结局信息。两次妊娠间隔时间为前次妊娠与本次妊娠末次月经之间的时长。影响妊娠间隔的最重要因素是前次分娩结局、社会阶层和母亲年龄。在考虑了这些变量后,我们发现两次妊娠间隔时间对死产率影响不大。然而,当两次妊娠间隔时间小于6个月时,新生儿死亡率较高(P<0.005),而较长的间隔时间则无显著影响。