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与噻嗪类药物使用相关的胰腺炎。甲状旁腺起作用了吗?

Pancreatitis associated with thiazide administration. A role for the parathyroid glands?

作者信息

Pickleman J, Straus F H, Paloyan E

出版信息

Arch Surg. 1979 Sep;114(9):1013-6. doi: 10.1001/archsurg.1979.01370330035006.

DOI:10.1001/archsurg.1979.01370330035006
PMID:485830
Abstract

Twenty-one of a total of 72 patients with acute pancreatitis admitted to a university hospital over a three-year period were found to have "idiopathic" pancreatitis. Of these, six nonalcoholic patients without gallbladder disease were receiving one of the thiazide diuretics prior to the onset of pancreatitis. Three patients taken from an earlier series likewise had pancreatitis associated with thiazide administration and at the time of autopsy harbored parathyroid hyperplasia. It is suggested that both the parathyroids and the pancreas may be affected by thiazide administration, and that a history of ingestion of these drugs should be sought in patients who have idiopathic pancreatitis.

摘要

在一所大学医院三年期间收治的72例急性胰腺炎患者中,有21例被发现患有“特发性”胰腺炎。其中,6例无胆囊疾病的非酒精性患者在胰腺炎发作前正在服用噻嗪类利尿剂之一。从较早系列中选取的3例患者同样患有与噻嗪类药物使用相关的胰腺炎,且尸检时伴有甲状旁腺增生。提示噻嗪类药物的使用可能会影响甲状旁腺和胰腺,对于患有特发性胰腺炎的患者,应询问其是否有服用这些药物的病史。

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Pancreatitis associated with thiazide administration. A role for the parathyroid glands?与噻嗪类药物使用相关的胰腺炎。甲状旁腺起作用了吗?
Arch Surg. 1979 Sep;114(9):1013-6. doi: 10.1001/archsurg.1979.01370330035006.
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Pancreas and Adverse Drug Reactions: A Literature Review.胰腺与药物不良反应:文献综述
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