噻嗪类利尿剂未能增加轻度原发性甲状旁腺功能亢进患者的血钙水平。
Failure of thiazide diuretics to increase plasma calcium in mild primary hyperparathyroidism.
作者信息
Farquhar C W, Spathis G S, Barron J L, Levin G E
机构信息
Department of Chemical Pathology, St. George's Hospital, London, UK.
出版信息
Postgrad Med J. 1990 Sep;66(779):714-6. doi: 10.1136/pgmj.66.779.714.
Abstract
Thirteen patients with mild primary hyperparathyroidism who were taking thiazide diuretics intermittently for periods of up to 18 months were followed up for a mean of 5.3 years. No significant difference was found in either plasma total calcium corrected for albumin or whole blood ionized calcium in these patients between the periods on or off thiazides. We conclude that thiazide diuretics are not contraindicated in such patients.
摘要
13例轻度原发性甲状旁腺功能亢进患者间歇性服用噻嗪类利尿剂长达18个月，平均随访5.3年。这些患者在服用或停用噻嗪类利尿剂期间，血浆总钙（经白蛋白校正）或全血离子钙均未发现显著差异。我们得出结论，此类患者使用噻嗪类利尿剂并无禁忌。
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