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Failure of thiazide diuretics to increase plasma calcium in mild primary hyperparathyroidism.噻嗪类利尿剂未能增加轻度原发性甲状旁腺功能亢进患者的血钙水平。
Postgrad Med J. 1990 Sep;66(779):714-6. doi: 10.1136/pgmj.66.779.714.
2
Thiazide diuretics and primary hyperparathyroidism.噻嗪类利尿剂与原发性甲状旁腺功能亢进症。
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Electrocardiographic J wave as a result of hypercalcemia aggravated by thiazide diuretics in a case of primary hyperparathyroidism.原发性甲状旁腺功能亢进症患者中，噻嗪类利尿剂加重高钙血症导致的心电图J波。
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Normocalcemic hyperparathyroidism.血钙正常的甲状旁腺功能亢进症。
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Hypercalcemia and primary hyperparathyroidism. Prevalence in patients receiving thiazides as detected in a health screen.高钙血症与原发性甲状旁腺功能亢进症。健康筛查中接受噻嗪类药物治疗患者的患病率。
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Thiazide therapy and severe hypercalcemia in a patient with hyperparathyroidism.一名甲状旁腺功能亢进患者的噻嗪类药物治疗与严重高钙血症
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[Nephrolithiasis in hypercalciuria and hyperparathyroidism].高钙尿症和甲状旁腺功能亢进中的肾结石病
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本文引用的文献

1
Primary hyperparathyroidism and thiazide diuretics.原发性甲状旁腺功能亢进症与噻嗪类利尿剂
Postgrad Med J. 1981 Feb;57(664):80-3. doi: 10.1136/pgmj.57.664.80.
2
Idiopathic hypercalciuria and hyperparathyroidism.特发性高钙尿症和甲状旁腺功能亢进症。
Br Med J. 1970 Dec 5;4(5735):582-5. doi: 10.1136/bmj.4.5735.582.
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Thiazide-induced rise in serum calcium and magnesium in patients on maintenance hemodialysis.
Ann Intern Med. 1970 Jun;72(6):895-901. doi: 10.7326/0003-4819-72-6-895.
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Chlorothiazide-induced hypercalcemia in juvenile osteoporosis and hyperparathyroidism.
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The effect of bendroflumethiazide on total, ultrafiltrable and ionized calcium in serum in normocalcaemic renal stone formers and in hyperparathyroidism.
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Hydrochlorothiazide effects on serum calcim and immunoreactive parathyroid hormone concentrations. Studies in normal subjects.
Ann Intern Med. 1972 Oct;77(4):587-91. doi: 10.7326/0003-4819-77-4-587.
7
changes in serum and urinary calcium during treatment with hydrochlorothiazide: studies on mechanisms.氢氯噻嗪治疗期间血清和尿钙的变化：作用机制研究
J Clin Invest. 1972 Apr;51(4):945-54. doi: 10.1172/JCI106889.
8
Prevention of calcium stones with thiazides.噻嗪类药物预防钙结石
Kidney Int. 1978 May;13(5):397-409. doi: 10.1038/ki.1978.58.

噻嗪类利尿剂未能增加轻度原发性甲状旁腺功能亢进患者的血钙水平。

Failure of thiazide diuretics to increase plasma calcium in mild primary hyperparathyroidism.

作者信息

Farquhar C W, Spathis G S, Barron J L, Levin G E

机构信息

Department of Chemical Pathology, St. George's Hospital, London, UK.

出版信息

Postgrad Med J. 1990 Sep;66(779):714-6. doi: 10.1136/pgmj.66.779.714.

DOI:10.1136/pgmj.66.779.714
PMID:2235800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2426866/
Abstract

Thirteen patients with mild primary hyperparathyroidism who were taking thiazide diuretics intermittently for periods of up to 18 months were followed up for a mean of 5.3 years. No significant difference was found in either plasma total calcium corrected for albumin or whole blood ionized calcium in these patients between the periods on or off thiazides. We conclude that thiazide diuretics are not contraindicated in such patients.

摘要

13例轻度原发性甲状旁腺功能亢进患者间歇性服用噻嗪类利尿剂长达18个月，平均随访5.3年。这些患者在服用或停用噻嗪类利尿剂期间，血浆总钙（经白蛋白校正）或全血离子钙均未发现显著差异。我们得出结论，此类患者使用噻嗪类利尿剂并无禁忌。