Weisberg L A
Arch Neurol. 1979 Oct;36(10):630-4. doi: 10.1001/archneur.1979.00500460064009.
Two-hundred consecutive patients with suspected metastatic carcinoma and signs of cerebral dysfunction were evaluated by computerized tomography (CT). In ten patients, CT defined a nonneoplastic disorder, whereas in 190, CT defined a metastatic neoplasm. In 70 of these patients, the lesion was solitary; in 120, the lesions were multiple. In 52 patients, plain scan showed a solitary lesion, but multiple lesions were seen after contrast scan. In nine patients, the abnormality was seen only on postcontrast scan. One hundred lesions were of low density and 87 showed enhancement; 81 were of high density, usually surrounded by a low-density rim, and 78 were enhanced. There were no characteristic CT patterns of specific systemic carcinomas, but epidermoid carcinoma frequently appeared as a low-density lesion with a thin peripheral enhancing rim, and adenocarcinoma appeared as a dense, homogeneous, round, enhancing nodule. After treatment, enhancement was the most reliable sign of residual or recurrent tumor.
对200例疑似转移性癌且有脑功能障碍体征的连续患者进行了计算机断层扫描（CT）评估。10例患者CT显示为非肿瘤性疾病，而190例患者CT显示为转移性肿瘤。其中70例患者为单发病变；120例患者为多发病变。52例患者平扫显示为单发病变，但增强扫描后可见多发病变。9例患者仅在增强扫描后发现异常。100个病变为低密度，87个有强化；81个为高密度，通常周围有低密度环，78个有强化。没有特定系统癌的特征性CT表现，但表皮样癌常表现为低密度病变，周边有薄的强化环，腺癌表现为致密、均匀、圆形、强化结节。治疗后，强化是残留或复发性肿瘤最可靠的征象。
