Anniko M, Eneroth P, Werner S, Wersäll J
Acta Otolaryngol. 1979;88(5-6):424-31. doi: 10.3109/00016487909137188.
Three types of human pituitary adenomas--growth hormone producing, prolactin producing, as well as endocrinologically inactive ('chromophobe') tumours--were explanted to an in vitro system for organ culture. After one month, surviving hypophyseal cells demonstrated preserved hormone activity and no dedifferentiation of cell characteristics. During the first weeks in culture, close similarity existed between in vivo and in vitro conditions with regard to cell survival/cell morphology and physiological function/hormone release.
三种人类垂体腺瘤——生长激素分泌型、催乳素分泌型以及内分泌无活性（“嫌色细胞”）肿瘤——被移植到一个用于器官培养的体外系统中。一个月后，存活的垂体细胞表现出保留的激素活性，且细胞特征未发生去分化。在培养的最初几周，在细胞存活/细胞形态以及生理功能/激素释放方面，体内和体外条件之间存在密切相似性。
