钙离子与水溶液中甘氨胆酸盐胶束的相互作用。
The interaction of calcium ions with glycocholate micelles in aqueous solution.
作者信息
Williamson B W, Percy-Robb I W
出版信息
Biochem J. 1979 Jul 1;181(1):61-6. doi: 10.1042/bj1810061.
Abstract
The formation of soluble complexes of Ca2+ ions and glycocholate has been demonstrated. The dissociation constant is 26 nmol/litre and a maximum of 2 Ca2+ ions are bound to each glycocholate micelle. The formation of this complex is shown to be reversible. Binding is increased by the introduction of phosphatidylcholine into the micelle; it is decreased by a decrease in pH and by increased counter-ion concentration. The biological significance of these effects is discussed.
摘要
已证实钙离子与甘胆酸盐可形成可溶性复合物。其解离常数为26纳摩尔/升，每个甘胆酸盐微团最多结合2个钙离子。该复合物的形成显示为可逆过程。向微团中引入磷脂酰胆碱可增加结合；pH降低和反离子浓度增加则会减少结合。文中讨论了这些效应的生物学意义。
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