Suppr超能文献

酒石酸锑钠治疗尿路血吸虫病——定量评估

Urinary schistosomiasis treated with sodium antimony tartrate--a quantitative evaluation.

作者信息

Farid Z, Bassily S, Kent D C, Hassan A, Abdel-Wahab M F, Wissa J

出版信息

Br Med J. 1968 Sep 21;3(5620):713-4. doi: 10.1136/bmj.3.5620.713.

Abstract

Seventeen Egyptian male farm-workers aged 8 to 27 years infected with Schistosoma haematobium were given twice-weekly intravenous injections of sodium antimony tartrate in a dose of 0.5 g. (30 mg.) per 15 kg. body weight for 12 injections. Bell's egg-count technique was used to evaluate results on 24-hour urine collections before and at 1, 4, 8, and 12 weeks after treatment. Patients were considered to be cured only when there were no eggs in the urine when examined by the filtration-staining, miracidial-hatching, and 24-hour urinesediment examination methods.At the final follow-up 14 out of 17 patients were found not to be passing eggs in the urine-an 82% cure rate. The mean reduction in egg output in the remaining three patients was 99%. These results are superior to any reported for other antimony drugs.

摘要

17名年龄在8至27岁之间感染埃及血吸虫的埃及男性农场工人,每周接受两次静脉注射酒石酸锑钠,剂量为每15公斤体重0.5克(30毫克),共注射12次。采用贝尔氏虫卵计数技术,对治疗前以及治疗后1、4、8和12周采集的24小时尿液进行检测以评估疗效。只有当通过过滤染色、毛蚴孵化和24小时尿液沉淀物检查方法检查尿液中没有虫卵时,患者才被视为治愈。在最后一次随访中,发现17名患者中有14名尿液中不再有虫卵,治愈率为82%。其余三名患者的虫卵排出量平均减少了99%。这些结果优于其他锑类药物的任何报道。

相似文献

2
A comparative evaluation of the treatment of Schitosoma mansoni with niridazole and potassium antimony tartrate.
Trans R Soc Trop Med Hyg. 1972;66(1):119-24. doi: 10.1016/0035-9203(72)90058-2.
5
[A case of urinary schistosomiasis in a Japanese male].
Hinyokika Kiyo. 1984 Oct;30(10):1479-83.

引用本文的文献

1
Availability, Toxicology and Medical Significance of Antimony.锑的可用性、毒理学和医学意义。
Int J Environ Res Public Health. 2022 Apr 12;19(8):4669. doi: 10.3390/ijerph19084669.
3
Antimony toxicity.锑中毒。
Int J Environ Res Public Health. 2010 Dec;7(12):4267-77. doi: 10.3390/ijerph7124267. Epub 2010 Dec 20.

本文引用的文献

1
TWSB IN SCHISTOSOMA MANSONI INFECTIONS: A QUANTITATIVE EVALUATION.
Ann Trop Med Parasitol. 1964 Jun;58:219-23. doi: 10.1080/00034983.1964.11686235.
3
Astiban therapy of urinary schistosomiasis: a quantitative evaluation.
Ann Trop Med Parasitol. 1966 Jun;60(2):165-8. doi: 10.1080/00034983.1966.11686401.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验