Farid Z, Bassily S, Kent D C, Hassan A, Abdel-Wahab M F, Wissa J
Br Med J. 1968 Sep 21;3(5620):713-4. doi: 10.1136/bmj.3.5620.713.
Seventeen Egyptian male farm-workers aged 8 to 27 years infected with Schistosoma haematobium were given twice-weekly intravenous injections of sodium antimony tartrate in a dose of 0.5 g. (30 mg.) per 15 kg. body weight for 12 injections. Bell's egg-count technique was used to evaluate results on 24-hour urine collections before and at 1, 4, 8, and 12 weeks after treatment. Patients were considered to be cured only when there were no eggs in the urine when examined by the filtration-staining, miracidial-hatching, and 24-hour urinesediment examination methods.At the final follow-up 14 out of 17 patients were found not to be passing eggs in the urine-an 82% cure rate. The mean reduction in egg output in the remaining three patients was 99%. These results are superior to any reported for other antimony drugs.
17名年龄在8至27岁之间感染埃及血吸虫的埃及男性农场工人，每周接受两次静脉注射酒石酸锑钠，剂量为每15公斤体重0.5克（30毫克），共注射12次。采用贝尔氏虫卵计数技术，对治疗前以及治疗后1、4、8和12周采集的24小时尿液进行检测以评估疗效。只有当通过过滤染色、毛蚴孵化和24小时尿液沉淀物检查方法检查尿液中没有虫卵时，患者才被视为治愈。在最后一次随访中，发现17名患者中有14名尿液中不再有虫卵，治愈率为82%。其余三名患者的虫卵排出量平均减少了99%。这些结果优于其他锑类药物的任何报道。
