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一种用于DNA流体动力学剪切的计算机模型(吉布斯现象):第二部分。

A computer model for hydrodynamic shearing of DNA (Gibb's phenomenon): Part II.

作者信息

Iyengar S S, Quave S A

出版信息

Comput Programs Biomed. 1979 Sep;10(2):133-5. doi: 10.1016/0010-468x(79)90060-6.

Abstract

This paper presents an extension of the distribution proposed during hydrodynamic shearing of DNA. In the Fourier least square approximation of uniform random distribution or a square wave, Gibb's phenomena occur at the boundaries. The same behavior occurs at the boundaries of the DNA strands undergoing hydrodynamic shearing of DNA. This hypothesis is corroborated by results from a computer simulation of hydrodynamic shearing of DNA. The evidence helps confirm the kinetic experiments of Britten and Kohne [4]. Furthermore the results predict that sequence very near the end (0.2 LAMBDA) should be the most intact.

摘要

本文提出了DNA流体动力学剪切过程中所提出分布的一种扩展。在均匀随机分布或方波的傅里叶最小二乘近似中,吉布斯现象出现在边界处。在经历DNA流体动力学剪切的DNA链的边界处也会出现同样的现象。DNA流体动力学剪切的计算机模拟结果证实了这一假设。这些证据有助于证实布里顿和科恩的动力学实验[4]。此外,结果预测非常靠近末端(0.2λ)的序列应该是最完整的。

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