用于分析核酸杂交、热变性和凝胶电泳数据的计算机程序。
Computer programs for analysis of nucleic acid hybridization, thermal denaturation, and gel electrophoresis data.
作者信息
Murphy R F, Pearson W R, Bonner J
出版信息
Nucleic Acids Res. 1979 Aug 24;6(12):3911-21. doi: 10.1093/nar/6.12.3911.
Abstract
Computer programs for the analysis of data from techniques frequently used in nucleic acids research are described. In addition to calculating non-linear, least-squares solutions to equations describing these systems, the programs allow for data editing, normalization, plotting and storage, and are flexible and simple to use. Typical applications of the programs are described.
摘要
本文描述了用于分析核酸研究中常用技术所产生数据的计算机程序。除了计算描述这些系统的方程的非线性最小二乘解之外，这些程序还允许进行数据编辑、归一化、绘图和存储，并且灵活易用。文中还介绍了这些程序的典型应用。
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Theory of the effects of concentration and chain length on helix-coil equilibria in two-stranded nucleic acids.双链核酸中浓度和链长对螺旋-线圈平衡影响的理论
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