Burdman J A, Szijan I, Jahn G A, Machiavelli G, Kalbermann L E
Experientia. 1979 Sep 15;35(9):1258-9. doi: 10.1007/BF01963324.
Sulpiride administration to rats releases prolactin and increases DNA replication in the anterior pituitary gland. Clomiphene prevents the stimulation of DNA synthesis produced by sulpiride, but does not affect prolactin release from the gland. These findings suggest that the intracellular prolactin content of the anterior pituitary gland plays a role in the regulation of DNA synthesis through a mechanism mediated by oestrogens.
给大鼠服用舒必利会释放催乳素并增加垂体前叶的DNA复制。氯米芬可阻止舒必利对DNA合成的刺激，但不影响该腺体释放催乳素。这些发现表明，垂体前叶细胞内的催乳素含量通过雌激素介导的机制在DNA合成的调节中发挥作用。
