Berger H, Warren A J, Fry K E
J Virol. 1969 Feb;3(2):171-5. doi: 10.1128/JVI.3.2.171-175.1969.
Recombination experiments were performed to assess the affect of amber mutations in 12 genes of T4D bacteriophage on genetic recombination. Crosses were performed in various suppressor-containing bacterial hosts to permit the production of progeny phage. Amber mutations in genes 32, 46, and 47 caused decreased recombination, amber mutations in genes 30, 41, 42, 43, 56, 61, and 62 caused increased recombination, whereas mutations in genes 63 and 37 showed no demonstrable effect on recombination.
进行了重组实验,以评估T4D噬菌体12个基因中的琥珀突变对基因重组的影响。在各种含有抑制基因的细菌宿主中进行杂交,以产生子代噬菌体。基因32、46和47中的琥珀突变导致重组减少,基因30、41、42、43、56、61和62中的琥珀突变导致重组增加,而基因63和37中的突变对重组没有明显影响。