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感染2型腺病毒的细胞的电子显微镜检查。

Electron microscopy of cells infected with adenovirus type 2.

作者信息

Weber J, Stich H F

出版信息

J Virol. 1969 Feb;3(2):198-204. doi: 10.1128/JVI.3.2.198-204.1969.

DOI:10.1128/JVI.3.2.198-204.1969
PMID:4886655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC375752/
Abstract

An electron microscope study of two strains of human adenovirus type 2 revealed the production of intranuclear paracrystalline formations by one of the strains. The crystals were composed of cylindrical tubules 25.0 nm in diameter arranged in a crystalline lattice with a periodicity of 75.0 nm. They appeared at 36 hr postinfection in nuclei which contained viral particles. Prolonged treatment with proteolytic enzyme only partially digested the crystals. The relationship of these crystals to similar nonviral crystals found in association with other virus infected-cells was discussed.

摘要

对两株人腺病毒2型进行的电子显微镜研究显示，其中一株产生了核内准晶体结构。这些晶体由直径为25.0纳米的圆柱形小管组成，排列成周期性为75.0纳米的晶格。它们在感染后36小时出现在含有病毒颗粒的细胞核中。用蛋白水解酶长时间处理只能部分消化这些晶体。讨论了这些晶体与在其他病毒感染细胞中发现的类似非病毒晶体的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/8fa81f46bb30/jvirol00302-0105-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/f82329b62769/jvirol00302-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/35fcfa66f167/jvirol00302-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/4fac896a15c6/jvirol00302-0103-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/899ee8440e81/jvirol00302-0103-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/ef073cc9f51a/jvirol00302-0103-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/6268aa1bf07f/jvirol00302-0105-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/d5139f60fe2d/jvirol00302-0105-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/8fa81f46bb30/jvirol00302-0105-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/f82329b62769/jvirol00302-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/35fcfa66f167/jvirol00302-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/4fac896a15c6/jvirol00302-0103-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/899ee8440e81/jvirol00302-0103-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/ef073cc9f51a/jvirol00302-0103-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/6268aa1bf07f/jvirol00302-0105-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/d5139f60fe2d/jvirol00302-0105-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089b/375752/8fa81f46bb30/jvirol00302-0105-c.jpg

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A correlative study by electron and light microscopy of the development of type 5 adenovirus. I. Electron microscopy.5型腺病毒发育的电子显微镜与光学显微镜相关研究。I. 电子显微镜观察
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Electron microscopic and histochemical studies of an unusual crystalline protein occurring in cells infected by type 5 adenovirus.
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Genetic Analysis of Adenovirus Type 2 II. Preliminary Phenotypic Characterization of Temperature-Sensitive Mutants.2型腺病毒的遗传分析。二、温度敏感突变体的初步表型特征分析。
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J Virol. 1971 Dec;8(6):842-9. doi: 10.1128/JVI.8.6.842-849.1971.
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