Inouye M, Guthrie J P
Proc Natl Acad Sci U S A. 1969 Nov;64(3):957-61. doi: 10.1073/pnas.64.3.957.
A temperature-sensitive mutant of E. coli, which cannot synthesize DNA at high temperature but can continue cell division, shows a difference in a membrane protein fraction at high temperature by gel electrophoresis. This mutation of a bacterial membrane protein is unique. The protein may link DNA replication and cell division through the membrane.
一种大肠杆菌的温度敏感突变体,在高温下不能合成DNA但能继续细胞分裂,通过凝胶电泳显示在高温下其膜蛋白组分存在差异。这种细菌膜蛋白的突变是独特的。该蛋白可能通过膜将DNA复制和细胞分裂联系起来。