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大肠杆菌的耐大肠杆菌素突变体:细胞膜对大肠杆菌素E1的抗性

Colicin-tolerant mutants of Escherichia coli: resistance of membranes to colicin E1.

作者信息

Bhattacharyya P, Wendt L, Whitney E, Silver S

出版信息

Science. 1970 May 22;168(3934):998-1000. doi: 10.1126/science.168.3934.998.

Abstract

Colicin E1 blocks proline accumulation by membrane vesicles prepared from wild-type sensitive Escherichia coli. Two classes of mutant cells are unaffected by colicin. Vesicles from colicin-resistant strains are sensitive to colicin E1, whereas vesicles from colicin-tolerant strains are unaffected by colicin El. These results suggest that the colicin E1 receptor is on the cell membrane and that colicin-tolerant strains have altered membranes while colicin-resistant strains have altered cell walls.

摘要

大肠杆菌素E1可阻止从野生型敏感大肠杆菌制备的膜囊泡积累脯氨酸。两类突变细胞不受大肠杆菌素影响。来自抗大肠杆菌素菌株的膜囊泡对大肠杆菌素E1敏感,而来自耐大肠杆菌素菌株的膜囊泡不受大肠杆菌素E1影响。这些结果表明,大肠杆菌素E1受体位于细胞膜上,耐大肠杆菌素菌株的膜发生了改变,而抗大肠杆菌素菌株的细胞壁发生了改变。

相似文献

1
Colicin-tolerant mutants of Escherichia coli: resistance of membranes to colicin E1.
Science. 1970 May 22;168(3934):998-1000. doi: 10.1126/science.168.3934.998.
2
Colicin E1-induced membrane de-energization in Escherichia coli [proceedings].
Biochem Soc Trans. 1979 Oct;7(5):1145-7. doi: 10.1042/bst0071145.
3
Demonstration of missing membrane proteins in a colicin-tolerant mutant of E. coli K12.
Biochem Biophys Res Commun. 1971 Aug 20;44(4):767-73. doi: 10.1016/0006-291x(71)90776-5.
7
Possibility of use of colicin-refractory mutants in the study of localization of colicin receptors.
Folia Microbiol (Praha). 1971;16(6):481-4. doi: 10.1007/BF02872724.

引用本文的文献

1
Active Transport of Manganese in Isolated Membranes of Escherichia coli.
J Bacteriol. 1970 Dec;104(3):1307-11. doi: 10.1128/jb.104.3.1307-1311.1970.
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Mechanism of colicin action: early events.
J Bacteriol. 1970 Dec;104(3):1236-41. doi: 10.1128/jb.104.3.1236-1241.1970.
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J Bacteriol. 1983 Feb;153(2):693-9. doi: 10.1128/jb.153.2.693-699.1983.
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Nature and properties of a Staphylococcus epidermidis bacteriocin.
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Possibility of use of colicin-refractory mutants in the study of localization of colicin receptors.
Folia Microbiol (Praha). 1971;16(6):481-4. doi: 10.1007/BF02872724.

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