• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Origin and direction of replication of the chromosome of E. coli B-r.大肠杆菌B-r染色体的复制起点与方向
Proc Natl Acad Sci U S A. 1970 Mar;65(3):601-8. doi: 10.1073/pnas.65.3.601.
2
The frequency of P1 transduction of the genes of Escherichia coli as a function of chromosomal position: preferential transduction of the origin of replication.大肠杆菌基因的P1转导频率作为染色体位置的函数：复制起点的优先转导。
Mol Gen Genet. 1977 Oct 20;155(2):197-202. doi: 10.1007/BF00393160.
3
Terminus region of the chromosome in Escherichia coli inhibits replication forks.大肠杆菌中染色体的末端区域会抑制复制叉。
Proc Natl Acad Sci U S A. 1977 Sep;74(9):3927-31. doi: 10.1073/pnas.74.9.3927.
4
Origin of replication, oriC, or the Escherichia coli chromosome on specialized transducing phages lambda asn.复制起点oriC，或专门转导噬菌体λ asn上的大肠杆菌染色体。
Mol Gen Genet. 1978 Apr 17;160(3):287-95. doi: 10.1007/BF00332972.
5
On the origin and direction of replication of the E. coli chromosome.关于大肠杆菌染色体复制的起源和方向
Cold Spring Harb Symp Quant Biol. 1968;33:575-84. doi: 10.1101/sqb.1968.033.01.064.
6
Map location of the Escherichia coli origin of replication.大肠杆菌复制起点的图谱定位。
Mol Gen Genet. 1978 Nov 9;166(3):299-304. doi: 10.1007/BF00267622.
7
Origin of replication, oriC, of the Escherichia coli K12 chromosome: genetic mapping and minichromosome replication.大肠杆菌K12染色体复制起点oriC：基因定位与微型染色体复制
Cold Spring Harb Symp Quant Biol. 1979;43 Pt 1:121-8. doi: 10.1101/sqb.1979.043.01.018.
8
Bi-directional chromosomal replication in Salmonella typhimurium.鼠伤寒沙门氏菌中的双向染色体复制。
J Bacteriol. 1973 Jul;115(1):168-76. doi: 10.1128/jb.115.1.168-176.1973.
9
The origin and direction of replication of the chromosome of Escherichia coli B-r.大肠杆菌B-r染色体的复制起点与方向
Proc Natl Acad Sci U S A. 1968 Aug;60(4):1268-74. doi: 10.1073/pnas.60.4.1268.
10
Origin and direction of DNA synthesis in E. coli B-r.大肠杆菌B-r中DNA合成的起源与方向
Proc Natl Acad Sci U S A. 1969 Mar;62(3):881-6. doi: 10.1073/pnas.62.3.881.

引用本文的文献

1
The variation in frequency with which markers are transduced by phage P1 is primarily a result of discrimination during recombination.噬菌体P1转导标记物的频率变化主要是重组过程中发生筛选的结果。
Mol Gen Genet. 1980;180(3):585-9. doi: 10.1007/BF00268064.
2
Reduction of marker discrimination in transductional recombination.转导重组中标记物鉴别能力的降低。
Mol Gen Genet. 1984;196(1):85-90. doi: 10.1007/BF00334097.
3
Transductional analysis of chromosome replication time.染色体复制时间的转导分析。
Mol Gen Genet. 1987 Dec;210(2):288-93. doi: 10.1007/BF00325696.
4
A DNA fragment containing the groE genes can suppress mutations in the Escherichia coli dnaA gene.一个包含groE基因的DNA片段能够抑制大肠杆菌dnaA基因中的突变。
Mol Gen Genet. 1986 Mar;202(3):446-54. doi: 10.1007/BF00333275.
5
The effect of DnaA protein levels and the rate of initiation at oriC on transcription originating in the ftsQ and ftsA genes: in vivo experiments.DnaA蛋白水平及oriC处起始速率对ftsQ和ftsA基因转录的影响：体内实验
Mol Gen Genet. 1989 Apr;216(2-3):475-83. doi: 10.1007/BF00334393.
6
Strains of Escherichia coli diploid for the chromosomal origin of DNA replication.具有DNA复制染色体起源的大肠杆菌二倍体菌株。
Mol Gen Genet. 1975 Dec 30;143(1):105-11. doi: 10.1007/BF00269427.
7
The frequency of P1 transduction of the genes of Escherichia coli as a function of chromosomal position: preferential transduction of the origin of replication.大肠杆菌基因的P1转导频率作为染色体位置的函数：复制起点的优先转导。
Mol Gen Genet. 1977 Oct 20;155(2):197-202. doi: 10.1007/BF00393160.
8
Evidence that F' lac replicates asynchronously during the cell cycle of Escherichia coli B/r.有证据表明F' lac在大肠杆菌B/r的细胞周期中进行异步复制。
Mol Gen Genet. 1978 Jul 11;163(2):205-12. doi: 10.1007/BF00267411.

本文引用的文献

1
THE REPLICATION OF DNA IN ESCHERICHIA COLI.大肠杆菌中DNA的复制
Proc Natl Acad Sci U S A. 1958 Jul 15;44(7):671-82. doi: 10.1073/pnas.44.7.671.
2
A method for securing thymineless mutants from strains of E. coli.一种从大肠杆菌菌株中获得无胸腺嘧啶突变体的方法。
Z Vererbungsl. 1961;92:403-12. doi: 10.1007/BF00890061.
3
SEQUENTIAL REPLICATION OF THE BACILLUS SUBTILIS CHROMOSOME. 3. REGULATION OF INITIATION.枯草芽孢杆菌染色体的连续复制。3. 起始调控。
Proc Natl Acad Sci U S A. 1964 Oct;52(4):973-80. doi: 10.1073/pnas.52.4.973.
4
THE EFFECT OF AMINO ACID DEPRIVATION ON SUBSEQUENT DEOXYRIBONUCLEIC ACID REPLICATION.氨基酸剥夺对后续脱氧核糖核酸复制的影响。
Biochim Biophys Acta. 1963 Sep 17;76:9-24.
5
The bacterial chromosome and its manner of replication as seen by autoradiography.通过放射自显影观察到的细菌染色体及其复制方式。
J Mol Biol. 1963 Mar;6:208-13. doi: 10.1016/s0022-2836(63)80070-4.
6
Sequential replication of Bacillus subtilis chromosome. I. Comparison of marker frequencies in exponential and stationary growth phases.枯草芽孢杆菌染色体的顺序复制。I. 指数生长期和稳定生长期标记频率的比较。
Proc Natl Acad Sci U S A. 1963 Apr;49(4):559-66. doi: 10.1073/pnas.49.4.559.
7
The molecular synchrony and sequential replication of DNA in Escherichia coli.大肠杆菌中DNA的分子同步性和序列复制
Proc Natl Acad Sci U S A. 1963 Apr;49(4):551-9. doi: 10.1073/pnas.49.4.551.
8
Selecting bacterial mutants by the penicillin method.用青霉素法筛选细菌突变体。
Science. 1960 Feb 26;131(3400):604-5. doi: 10.1126/science.131.3400.604.
9
Beta-galactosidase formation controlled by an episomal gene during the cell cycle of Escherichia coli.在大肠杆菌细胞周期中，由附加体基因控制的β-半乳糖苷酶形成。
J Biochem. 1966 Sep;60(3):338-40. doi: 10.1093/oxfordjournals.jbchem.a128442.
10
Evidence for polarity of chromosome replication in F- strains of Escherichia coli.大肠杆菌F-菌株中染色体复制极性的证据。
Genet Res. 1966 Aug;8(1):119-24. doi: 10.1017/s0016672300009976.

大肠杆菌B-r染色体的复制起点与方向

Origin and direction of replication of the chromosome of E. coli B-r.

作者信息

Masters M

出版信息

Proc Natl Acad Sci U S A. 1970 Mar;65(3):601-8. doi: 10.1073/pnas.65.3.601.

DOI:10.1073/pnas.65.3.601
PMID:4910849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC282949/
Abstract

The origin and direction of replication of the E. coli B/r chromosome has been determined by comparing gene frequencies in P1-transducing lysates prepared on cultures growing at different rates. The gene frequencies found are consistent with the idea that replication of the chromosome is dichotomous in rapidly growing B/r. The origin was found to be between 40 and 55 min on the E. coli genetic map with replication proceeding in a clockwise direction. Markers near the origin behaved anomalously.

摘要

通过比较在不同生长速率的培养物上制备的P1转导裂解物中的基因频率，已确定了大肠杆菌B/r染色体的复制起点和方向。所发现的基因频率与快速生长的B/r中染色体复制是二分体的观点一致。发现起点位于大肠杆菌遗传图谱上40至55分钟之间，复制按顺时针方向进行。靠近起点的标记表现异常。