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噬菌体感染的鼠伤寒沙门氏菌中L-阿拉伯糖异构酶的诱导与抑制

Induction and repression of L-arabinose isomerase in bacteriophage-infected Salmonella typhimurium.

作者信息

Chakravorty M

出版信息

J Virol. 1970 May;5(5):541-7. doi: 10.1128/JVI.5.5.541-547.1970.

Abstract

The induction of l-arabinose isomerase in Salmonella typhimurium (LT2) is repressed on infection with clear plaque forming mutants (C(1) and C(2)) of the temperate phage P22 (C(+)). However, after infection with C(+) leading to lysogeny, there is a temporary repression. During this period, messenger ribonucleic acid (RNA) for l-arabinose isomerase accumulates. DNA-RNA hybridization data suggest that there is transcription of host DNA during the period of repression. Interference at the level of translation might be responsible for the cessation of induced enzyme synthesis.

摘要

鼠伤寒沙门氏菌(LT2)中L-阿拉伯糖异构酶的诱导在被温和噬菌体P22(C(+))的清晰噬菌斑形成突变体(C(1)和C(2))感染时受到抑制。然而,在被C(+)感染导致溶原化后,会有一个短暂的抑制期。在此期间,L-阿拉伯糖异构酶的信使核糖核酸(RNA)会积累。DNA-RNA杂交数据表明,在抑制期宿主DNA会发生转录。翻译水平的干扰可能是诱导酶合成停止的原因。

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