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磷酸烯醇丙酮酸磷酸转移酶系统在大肠杆菌转运N-乙酰-D-葡萄糖胺中的作用。

The role of the phosphoenolpyruvate phosphotransferase system in the transport of N-acetyl-D-glucosamine by Escherichia coli.

作者信息

White R J

出版信息

Biochem J. 1970 Jun;118(1):89-92. doi: 10.1042/bj1180089.

DOI:10.1042/bj1180089
PMID:4919472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1179084/
Abstract

The properties of an N-acetyl-d-glucosamine-transport system have been studied by following the intracellular accumulation of methyl 2-acetamido-2-deoxy-alpha-d-[1-(14)C]glucoside by Escherichia coli. The same analogue was used to assay phosphoenolpyruvate phosphotransferase activity of toluene-treated cells. Transport and phosphorylation are induced by growth on d-glucosamine or N-acetyl-d-glucosamine. Mutants resistant to N-iodoacetyl-d-glucosamine are defective in the uptake and phosphorylation of the labelled glycoside.

摘要

通过追踪大肠杆菌对甲基2-乙酰氨基-2-脱氧-α-D-[1-(14)C]葡萄糖苷的细胞内积累情况，对N-乙酰-D-葡萄糖胺转运系统的特性进行了研究。使用相同的类似物来测定经甲苯处理的细胞的磷酸烯醇丙酮酸磷酸转移酶活性。在D-葡萄糖胺或N-乙酰-D-葡萄糖胺上生长可诱导转运和磷酸化。对N-碘代乙酰-D-葡萄糖胺具有抗性的突变体在标记糖苷的摄取和磷酸化方面存在缺陷。

相似文献

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The role of the phosphoenolpyruvate phosphotransferase system in the transport of N-acetyl-D-glucosamine by Escherichia coli.磷酸烯醇丙酮酸磷酸转移酶系统在大肠杆菌转运N-乙酰-D-葡萄糖胺中的作用。
Biochem J. 1970 Jun;118(1):89-92. doi: 10.1042/bj1180089.
2
N-iodoacetyl-D-glucosamine, an inhibitor of growth and glycoside uptake in Escherichia coli.N-碘乙酰-D-葡萄糖胺，一种大肠杆菌生长和糖苷摄取的抑制剂。
Biochem J. 1970 Jun;118(1):73-9. doi: 10.1042/bj1180073.
3
An examination of the inhibitory effects of N-iodoacetylglucosamine on Escherichia coli and isolation of resistant mutants.N-碘乙酰葡糖胺对大肠杆菌的抑制作用研究及抗性突变体的分离
Biochem J. 1970 Jun;118(1):81-7. doi: 10.1042/bj1180081.
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本文引用的文献

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Galactose transport in Escherichia coli. III. The effect of 2,4-dinitrophenol on entry and accumulation.大肠杆菌中的半乳糖转运。III. 2,4-二硝基苯酚对进入和积累的影响。
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PHOSPHATE BOUND TO HISTIDINE IN A PROTEIN AS AN INTERMEDIATE IN A NOVEL PHOSPHO-TRANSFERASE SYSTEM.蛋白质中与组氨酸结合的磷酸盐作为新型磷转移酶系统中的中间体。
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STUDIES ON THE GLUCOSE-TRANSPORT SYSTEM IN ESCHERICHIA COLI WITH ALPHA-METHYLGLUCOSIDE AS SUBSTRATE.以α-甲基葡萄糖苷为底物对大肠杆菌葡萄糖转运系统的研究。
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Mechanism of hydrolysis of O-nitrophenyl-beta-galactoside in Staphylococcus aureus and its significance for theories of sugar transport.金黄色葡萄球菌中O-硝基苯基-β-半乳糖苷的水解机制及其对糖转运理论的意义。
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The role of energy coupling in the transport of beta-galactosides by Escherichia coli.能量偶联在大肠杆菌转运β-半乳糖苷中的作用。
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