组氨酰转移核糖核酸与鼠伤寒沙门氏菌组氨酸生物合成的第一种酶之间的相互作用。
Interaction between histidyl transfer ribonucleic acid and the first enzyme for histidine biosynthesis of Salmonella typhimurium.
作者信息
Kovach J S, Phang J M, Blasi F, Barton R W, Ballesteros-Olmo A, Goldberger R F
出版信息
J Bacteriol. 1970 Nov;104(2):787-92. doi: 10.1128/jb.104.2.787-792.1970.
Abstract
Previous studies showed that the enzyme (phosphoribosyltransferase) which catalyzes the first step of the histidine pathway in Salmonella typhimurium plays a role in regulation of the histidine operon. Since histidyl transfer ribonucleic acid (His-tRNA) is required for repression of the histidine operon, we considered the possibility that the role of phosphoribosyltransferase might be realized through an interaction with His-tRNA. One prediction inherent in this idea is that the enzyme should interact with His-tRNA in vitro. Evidence is presented for such an interaction. Binding of (3)H-His-tRNA to purified phosphoribosyltransferase was tested on Sephadex columns and on nitrocellulose filters. The enzyme was found to have a high affinity for tRNA. Comparing the binding of (3)H-His-tRNA with that of tRNA aminoacylated with other (3)H-amino acids disclosed that the binding of the histidyl species of tRNA is favored over that of other species and is dependent upon magnesium-ion concentration.
摘要
先前的研究表明，在鼠伤寒沙门氏菌中催化组氨酸途径第一步的酶（磷酸核糖基转移酶）在组氨酸操纵子的调控中发挥作用。由于组氨酸操纵子的阻遏需要组氨酰转移核糖核酸（His - tRNA），我们考虑了磷酸核糖基转移酶的作用可能通过与His - tRNA相互作用来实现的可能性。这个想法中固有的一个预测是，该酶在体外应该与His - tRNA相互作用。本文提供了这种相互作用的证据。在葡聚糖凝胶柱和硝酸纤维素滤膜上测试了³H - His - tRNA与纯化的磷酸核糖基转移酶的结合。发现该酶对tRNA具有高亲和力。将³H - His - tRNA的结合与用其他³H - 氨基酸氨酰化的tRNA的结合进行比较，结果表明tRNA的组氨酰种类的结合比其他种类更受青睐，并且依赖于镁离子浓度。
相似文献
1
Interaction between histidyl transfer ribonucleic acid and the first enzyme for histidine biosynthesis of Salmonella typhimurium.组氨酰转移核糖核酸与鼠伤寒沙门氏菌组氨酸生物合成的第一种酶之间的相互作用。
J Bacteriol. 1970 Nov;104(2):787-92. doi: 10.1128/jb.104.2.787-792.1970.
2
Interaction between the first enzyme for histidine biosynthesis and histidyl transfer ribonucleic acid.组氨酸生物合成的第一种酶与组氨酰转移核糖核酸之间的相互作用。
J Bacteriol. 1971 May;106(2):508-13. doi: 10.1128/jb.106.2.508-513.1971.
3
First enzyme of histidine biosynthesis and repression control of histidyl-transfer ribonucleic acid synthetase of Salmonella typhimurium.鼠伤寒沙门氏菌组氨酸生物合成的首个酶以及组氨酰转移核糖核酸合成酶的阻遏控制
J Bacteriol. 1974 Oct;120(1):390-3. doi: 10.1128/jb.120.1.390-393.1974.
4
Interaction between phosphoribosyltransferase and purified histidine tRNA from wild type Salmonella typhimurium and a derepressed hisT mutant strain.磷酸核糖基转移酶与野生型鼠伤寒沙门氏菌及去阻遏hisT突变株纯化的组氨酸tRNA之间的相互作用。
Nucleic Acids Res. 1975 Apr;2(4):545-54. doi: 10.1093/nar/2.4.545.
5
Specificity of interaction between the first enzyme for histidine biosynthesis and aminoacylated histidine transfer ribonucleic acid.组氨酸生物合成的首个酶与氨酰化组氨酸转移核糖核酸之间相互作用的特异性。
J Bacteriol. 1972 Oct;112(1):126-30. doi: 10.1128/jb.112.1.126-130.1972.
6
7
Role of histidine transfer ribonucleic acid in regulation of synthesis of histidyl-transfer ribonucleic acid synthetase of Salmonella typhimurium.组氨酸转移核糖核酸在鼠伤寒沙门氏菌组氨酰转移核糖核酸合成酶合成调控中的作用。
J Bacteriol. 1972 Feb;109(2):505-11. doi: 10.1128/jb.109.2.505-511.1972.
8
Defective in vitro binding of histidyl-transfer ribonucleic acid to feedback resistant phosphoribosyl transferase of Salmonella typhimurium.组氨酰转运核糖核酸与鼠伤寒沙门氏菌反馈抗性磷酸核糖转移酶的体外结合存在缺陷。
Nucleic Acids Res. 1974 Jul;1(7):881-8. doi: 10.1093/nar/1.7.881.
9
10
Histidyl-transfer ribonucleic acid synthetase in positive control of the histidine operon in Salmonella typhimurium.组氨酰转移核糖核酸合成酶对鼠伤寒沙门氏菌中组氨酸操纵子的正调控。
J Bacteriol. 1974 Feb;117(2):708-16. doi: 10.1128/jb.117.2.708-716.1974.
引用本文的文献
1
A DnaA-dependent riboswitch for transcription attenuation of the operon.一种依赖DnaA的核糖开关，用于操纵子的转录衰减。
mLife. 2023 Jun 30;2(2):126-140. doi: 10.1002/mlf2.12075. eCollection 2023 Jun.
2
Defective in vitro binding of histidyl-transfer ribonucleic acid to feedback resistant phosphoribosyl transferase of Salmonella typhimurium.组氨酰转运核糖核酸与鼠伤寒沙门氏菌反馈抗性磷酸核糖转移酶的体外结合存在缺陷。
Nucleic Acids Res. 1974 Jul;1(7):881-8. doi: 10.1093/nar/1.7.881.
3
An aminoacyl-tRNA synthetase paralog with a catalytic role in histidine biosynthesis.一种在组氨酸生物合成中具有催化作用的氨酰-tRNA合成酶旁系同源物。
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8985-90. doi: 10.1073/pnas.96.16.8985.
4
Possible regulation of the Salmonella typhimurium histidine operon by adenosine triphosphate phosphoribosyltransferase: large metabolic effects.三磷酸腺苷磷酸核糖基转移酶对鼠伤寒沙门氏菌组氨酸操纵子的可能调控：巨大的代谢效应。
J Bacteriol. 1980 Oct;144(1):337-45. doi: 10.1128/jb.144.1.337-345.1980.
5
The leader mRNA of the histidine attenuator region resembles tRNAHis: possible general regulatory implications.组氨酸衰减子区域的前导mRNA类似于组氨酸转运RNA：可能具有普遍的调控意义。
Proc Natl Acad Sci U S A. 1983 Sep;80(17):5240-2. doi: 10.1073/pnas.80.17.5240.
6
Interaction between the first enzyme for histidine biosynthesis and histidyl transfer ribonucleic acid.组氨酸生物合成的第一种酶与组氨酰转移核糖核酸之间的相互作用。
J Bacteriol. 1971 May;106(2):508-13. doi: 10.1128/jb.106.2.508-513.1971.
7
Autoregulation: a role for a biosynthetic enzyme in the control of gene expression.自调节：一种生物合成酶在基因表达调控中的作用。
Proc Natl Acad Sci U S A. 1973 Oct;70(10):2757-61. doi: 10.1073/pnas.70.10.2757.
8
Inhibition of transcription of the histidine operon in vitro by the first enzyme of the histidine pathway.组氨酸途径的第一种酶对组氨酸操纵子体外转录的抑制作用。
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2692-6. doi: 10.1073/pnas.70.9.2692.
9
Relationships among deoxyribonucleic acid, ribonucleic acid, and specific transfer ribonucleic acids in Escherichia coli 15T - at various growth rates.大肠杆菌15T - 不同生长速率下脱氧核糖核酸、核糖核酸和特定转移核糖核酸之间的关系
J Bacteriol. 1973 Jul;115(1):177-87. doi: 10.1128/jb.115.1.177-187.1973.
10
Restoration of phosphoribosyl transferase activity by partially deleting the trpB gene in the tryptophan operon of Salmonella typhimurium.通过部分缺失鼠伤寒沙门氏菌色氨酸操纵子中的trpB基因来恢复磷酸核糖转移酶活性。
J Bacteriol. 1972 Nov;112(2):877-85. doi: 10.1128/jb.112.2.877-885.1972.
本文引用的文献
1
COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE.组氨酸对四种组氨酸生物合成酶合成的协同抑制作用
Proc Natl Acad Sci U S A. 1959 Oct;45(10):1453-61. doi: 10.1073/pnas.45.10.1453.
2
GENES AND PROTEINS INVOLVED IN HISTIDINE BIOSYNTHESIS IN SALMONELLA.参与沙门氏菌组氨酸生物合成的基因和蛋白质
Brookhaven Symp Biol. 1964 Dec;17:15-52.
3
MUTANTS OF SALMONELLA TYPHIMURIUM RESISTANT TO FEEDBACK INHIBITION BY L-HISTIDINE.鼠伤寒沙门氏菌对L-组氨酸反馈抑制具有抗性的突变体
Genetics. 1964 Oct;50(4):611-23. doi: 10.1093/genetics/50.4.611.
4
EFFECT OF ALPHA-METHYLHISTIDINE ON THE CONTROL OF HISTIDINE SYNTHESIS.α-甲基组氨酸对组氨酸合成调控的影响。
J Mol Biol. 1964 Sep;9:670-82. doi: 10.1016/s0022-2836(64)80174-1.
5
Chromosomal alterations affecting the regulation of histidine biosynthetic enzymes in Salmonella.影响沙门氏菌中组氨酸生物合成酶调控的染色体改变。
J Mol Biol. 1963 Jul;7:23-42. doi: 10.1016/s0022-2836(63)80016-9.
6
Measurement of protein-binding phenomena by gel filtration.通过凝胶过滤法测定蛋白质结合现象。
Biochim Biophys Acta. 1962 Oct 8;63:530-2. doi: 10.1016/0006-3002(62)90124-5.
7
The genetic control of the enzymes of histidine biosynthesis in Salmonella typhimurium.鼠伤寒沙门氏菌中组氨酸生物合成酶的遗传控制
J Gen Microbiol. 1960 Apr;22:369-78. doi: 10.1099/00221287-22-2-369.
8
Interference with the feed-back control of histidine biosynthesis.对组氨酸生物合成反馈控制的干扰。
J Biol Chem. 1961 Aug;236:2261-7.
9
The first step of histidine biosynthesis.组氨酸生物合成的第一步。
J Biol Chem. 1961 Jul;236:2019-26.
10
Histidine regulatory mutants in Salmonella typhimurium 3. A class of regulatory mutants deficient in tRNA for histidine.鼠伤寒沙门氏菌中的组氨酸调节突变体3. 一类组氨酸tRNA缺乏的调节突变体。
J Mol Biol. 1966 Dec 28;22(2):335-47. doi: 10.1016/0022-2836(66)90136-7.
Zotero 插件