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噬菌体与C型肉毒梭菌的产毒性

Bacteriophage and the toxigenicity of Clostridium botulinum type C.

作者信息

Eklund M W, Poysky F T, Reed S M, Smith C A

出版信息

Science. 1971 Apr 30;172(3982):480-2. doi: 10.1126/science.172.3982.480.

DOI:10.1126/science.172.3982.480
PMID:4927679
Abstract

Nontoxigenic and bacteriophage-sensitive bacterial cultures have been isolated from toxigenic Clostridium botulinum type C, strain 468C, after treatment with either ultraviolet light or acridine orange. Two bacteriophages, designated CEbeta and CE(gamma), were isolated from toxigenic strain 468C. Both of these bacteriophages were capable of infecting the nontoxigenic type C cultures, but only bacteriophage CEbeta was involved in the change from nontoxigenicity to toxigenicity.

摘要

在用紫外线或吖啶橙处理产毒的C型肉毒梭菌468C菌株后,已从该菌株中分离出无毒且对噬菌体敏感的细菌培养物。从产毒菌株468C中分离出两种噬菌体,分别命名为CEβ和CEγ。这两种噬菌体都能够感染无毒的C型培养物,但只有噬菌体CEβ参与了从无毒到产毒的转变。

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