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肉毒梭菌C型通过噬菌体转化为诺维氏梭菌A型

Interspecies conversion of Clostridium botulinum type C to Clostridium novyi type A by bacteriophage.

作者信息

Eklund M W, Poysky F T, Meyers J A, Pelroy G A

出版信息

Science. 1974 Nov 1;186(4162):456-8. doi: 10.1126/science.186.4162.456.

DOI:10.1126/science.186.4162.456
PMID:4606682
Abstract

When Clostridium botulinum type C is cured of its prophage it simultaneously ceases to produce toxin. This nontoxigenic culture can then be converted to another toxigenic bacterial species, Clostridium novyi type A or to toxigenic Clostridium botulinum types C or D, by specific bacteriophages. The toxigenicity and type of toxin produced by these cultures depends upon the continued presence of these bacteriophages.

摘要

当C型肉毒梭菌的前噬菌体被去除后,它会同时停止产生毒素。这种非产毒培养物随后可以通过特定的噬菌体转化为另一种产毒细菌物种,即A型诺维梭菌,或转化为产毒的C型或D型肉毒梭菌。这些培养物产生毒素的能力和所产生毒素的类型取决于这些噬菌体的持续存在。

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