Cohen S A, Hendricks K M, Mathis R K, Laramee S, Walker W A
Pediatrics. 1979 Oct;64(4):402-7.
Chronic nonspecific diarrhea (CNSD) is the most common cause of prolonged diarrhea without failure to thrive. Although it is most commonly seen from ages 6 to 36 months, CNSD may persist until 54 months of age. Forty-four patients with this syndrome had complete dietary histories, and were divided into four groups on the basis of their intakes and responses to its modification. Each of the four groups had significantly less fat in their diet at the time of presentation than did ten non-CNSD patients (P less than .005) presenting similarly. In three of the groups, daily fat consumption was increased, irrespective of the adequacy of their initial intakes. In all 38 patients in these groups, this dietary modification was associated with the resolution of symptoms. The fourth group, with initially normal dietary fat ingestion, did not respond to dietary therapy. The overall success rate of the regimen in this patient population was 82%. Carbohydrate, fiber, and caloric contents of the diets did not appear to play as significant a role as fat intake.
慢性非特异性腹泻（CNSD）是导致长期腹泻且无生长发育迟缓的最常见原因。虽然CNSD最常见于6至36个月龄的儿童，但也可能持续到54个月龄。44例患有该综合征的患者有完整的饮食史，并根据其摄入量和对饮食调整的反应分为四组。与10例表现相似的非CNSD患者相比，这四组患者在就诊时饮食中的脂肪含量均显著较低（P小于0.005）。在其中三组中，无论初始摄入量是否充足，每日脂肪摄入量均有所增加。在这些组中的所有38例患者中，这种饮食调整都与症状缓解相关。第四组患者最初饮食脂肪摄入量正常，对饮食治疗无反应。该治疗方案在这群患者中的总体成功率为82%。饮食中的碳水化合物、纤维和热量含量似乎不如脂肪摄入量起的作用大。
