麻醉猫的胃蛋白酶分泌、胃动力及黏膜血流
Pepsin secretion, gastric motility and mucosal blood flow in the anaesthetized cat.
作者信息
Reed J D, Sanders D J
出版信息
J Physiol. 1971 Jul;216(1):159-70. doi: 10.1113/jphysiol.1971.sp009515.
Abstract
- There is a weak relationship between pepsin output and gastric mucosal blood flow (MBF) during vagal stimulation. When compared with the strong relationship between H(+) output and MBF, this suggests little dependence of pepsin secretion on MBF.2. Gastric MBF per unit H(+) output was significantly greater during vagal stimulation, when H(+) secretion was accompanied by pepsin secretion, than during pentapeptide stimulation when no pepsin was secreted.3. Pepsin output was not reduced during splanchnic stimulation whereas MBF and acid output were, when blood pressure was kept constant.4. Splanchnic stimulation did not produce any pepsin secretion.5. Gastric motor responses to vagal stimulation and to I.A. injections of acetylcholine were equally reduced by splanchnic stimulation.
摘要
迷走神经刺激期间，胃蛋白酶分泌量与胃黏膜血流量（MBF）之间的关系较弱。与氢离子分泌量和胃黏膜血流量之间的强关系相比，这表明胃蛋白酶分泌对胃黏膜血流量的依赖性较小。
迷走神经刺激期间，当氢离子分泌伴有胃蛋白酶分泌时，每单位氢离子分泌量的胃黏膜血流量显著大于五肽刺激期间（此时无胃蛋白酶分泌）。
当血压保持恒定时，内脏刺激期间胃蛋白酶分泌量未降低，而胃黏膜血流量和酸分泌量降低。
内脏刺激未产生任何胃蛋白酶分泌。
内脏刺激对迷走神经刺激和腹腔注射乙酰胆碱引起的胃运动反应的抑制作用相同。
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The effect of splanchnic nerve stimulation on gastric acid secretion and mucosal blood flow in the anaesthetized cat.内脏神经刺激对麻醉猫胃酸分泌及黏膜血流的影响。
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