新型低氧细胞放射增敏剂的研发与测试
Development and testing of new hypoxic cell radiosensitizers.
作者信息
Kimler B F, McDonald T, Cheng C C, Podrebarac E G, Mansfield C M
出版信息
Radiology. 1979 Nov;133(2):515-7. doi: 10.1148/133.2.515.
PMID:493545
Abstract
Several new electron-affinic compounds have been shown to possess radiosensitizing ability in hypoxic mammalian cells. The correlation between chemical structure and biological activity can aid in the design and synthesis of new agents with potentially greater hypoxic cell radiosensitizing ability.
摘要
几种新的亲电子化合物已被证明在缺氧的哺乳动物细胞中具有放射增敏能力。化学结构与生物活性之间的相关性有助于设计和合成具有潜在更强缺氧细胞放射增敏能力的新药物。
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