用丁苯那嗪治疗持续性吩噻嗪类药物所致运动障碍
Persistent phenothiazine dyskinesia treated with tetrabenazine.
作者信息
Godwin-Austen R B, Clark T
出版信息
Br Med J. 1971 Oct 2;4(5778):25-6. doi: 10.1136/bmj.4.5778.25.
Abstract
Six patients with persistent phenothiazine dyskinesia were treated in a double-blind controlled trial with tetrabenazine 100 mg in divided dosage. In three patients the abnormal movements were abolished and in two others there was some improvement, but this was no greater than that achieved with the diazepam control. Tetrabenazine may be useful in the treatment of some patients with persistent phenothiazine dyskinesia.
摘要
六名患有持续性吩噻嗪类药物所致运动障碍的患者参与了一项双盲对照试验，接受每日100毫克丁苯那嗪分剂量治疗。三名患者的异常运动消失，另外两名患者有一定改善，但改善程度不超过地西泮对照组。丁苯那嗪可能对治疗某些持续性吩噻嗪类药物所致运动障碍患者有效。
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