恶性疾病中的平滑肌抗体。
Smooth muscle antibody in malignant disease.
作者信息
Whitehouse J M, Holborow E J
出版信息
Br Med J. 1971 Nov 27;4(5786):511-3. doi: 10.1136/bmj.4.5786.511.
Abstract
Smooth muscle antibody at titres of 1/10 or more was found in 54 (67.5%) out of 80 patients with malignant disease and in 9 (20%) out of 46 controls. The incidence of S.M. antibody ranged from 18/30 (60%) in malignant melanoma to 7/8 (83%) in carcinoma of the ovary. The presence of this antibody is possibly related to changes in the malignant cell membrane.A new antibody directed at an antigen presumed to be located in bile canaliculi among other sites is described.
摘要
在80例恶性疾病患者中，54例（67.5%）检测到平滑肌抗体效价为1/10或更高，而在46例对照者中，9例（20%）检测到该抗体。平滑肌抗体的发生率在恶性黑色素瘤患者中为18/30（60%），在卵巢癌患者中为7/8（83%）。这种抗体的存在可能与恶性细胞膜的变化有关。本文描述了一种针对假定位于胆小管及其他部位的抗原的新抗体。
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