Leslie G A, Crandall R B, Crandall C A
Immunology. 1971 Dec;21(6):983-7.
Tissue sections from various areas of the digestive and respiratory tracts and spleens of chickens were examined by the fluorescent antibody technique for the presence of immunoglobulin-containing cells. All tissues examined contained lymphoid cells staining for immunoglobulin with the duodenum and caecal tonsils containing the highest concentrations of such cells. Spleens had approximately equal numbers of IgM- and IgY-containing cells; other tissues showed a predominance of IgY-containing cells. The distribution of IgY-containing cells in the chicken gastrointestinal tract was similar to that generally associated with the secretory immunologic system of mammals which shows a preponderance of IgA-containing cells. These results in conjunction with other available data suggest that the chicken has evolved a secretory immunological system wherein the predominant serum immunoglobulin and the secretory immunoglobulin belong to the same class.
运用荧光抗体技术检查鸡的消化和呼吸道各部位以及脾脏的组织切片，以确定含免疫球蛋白细胞的存在情况。所有检查的组织都含有对免疫球蛋白呈阳性染色的淋巴细胞，其中十二指肠和盲肠扁桃体所含此类细胞的浓度最高。脾脏中含IgM和含IgY的细胞数量大致相等；其他组织中含IgY的细胞占优势。鸡胃肠道中含IgY细胞的分布与通常和哺乳动物分泌免疫系统相关的分布情况相似，后者显示含IgA细胞占优势。这些结果与其他现有数据表明，鸡已经进化出一种分泌免疫系统，其中主要的血清免疫球蛋白和分泌免疫球蛋白属于同一类别。
