Vineis P, Aimone G, Costa G
Tumori. 1979 Aug 31;65(4):407-23. doi: 10.1177/030089167906500401.
Age-standardized incidence rates of Hodgkin's disease in the province of Torino in 1965-1971 were 2.81/100,000/year in males and 1.64 in females, i.e., somewhat lower than in urban areas of other industrialized countries. In the whole province, age-distribution for males was similar to previous findings elsewhere, with a young-adult peak at ages 25-34. However, in the city of Torino, males showed a first peak in the age-class 35-44, while in the rest of the province an infantile peak (0-14 years) was found. By dividing the latter area in suburbs and nonmetropolitan area, the infantile peak was confirmed only in the nonmetropolitan area. Females showed a different behavior: in the city of Torino there was a unimodal curve (peak in age-class 55-64), and in the rest of the province there was a bimodal curve with a first peak in age-class 15-24. These patterns have been analyzed in relation to the suggestion of a distribution by age of Hodgkin's disease following 3 types (nonindustrialized countries, urban areas of industrialized countries and rural areas of industrialized countries). No significant differences in the distribution of cases were found among the smallest geographical units considered (ULSs), in contrast with previous findings on cancer of the larynx and bladder, which showed marked geographical differences within the province of Torino.
1965 - 1971年期间，都灵省霍奇金病的年龄标准化发病率男性为2.81/10万/年，女性为1.64/10万/年，即略低于其他工业化国家的城市地区。在全省范围内，男性的年龄分布与其他地方先前的研究结果相似，在25 - 34岁出现青年成人发病高峰。然而，在都灵市，男性在35 - 44岁年龄组出现第一个高峰，而在该省其他地区则发现一个婴幼儿高峰（0 - 14岁）。将后一地区分为郊区和非都市地区后，仅在非都市地区确认了婴幼儿高峰。女性表现出不同的情况：在都灵市有一条单峰曲线（在55 - 64岁年龄组达到高峰），在该省其他地区有一条双峰曲线，第一个高峰在15 - 24岁年龄组。已根据霍奇金病按3种类型（非工业化国家、工业化国家的城市地区和工业化国家的农村地区）划分的年龄分布建议对这些模式进行了分析。在所考虑的最小地理单位（ULS）之间，病例分布未发现显著差异，这与先前关于喉癌和膀胱癌的研究结果形成对比，后者显示在都灵省内存在明显的地理差异。
