Terracini B, Anglesio E, Panero M, Vineis P
Tumori. 1978 Oct 31;64(5):445-56. doi: 10.1177/030089167806400501.
Age-standardized incidence rates of cancer of the larynx in men from 1965-1969 were 14.7/100,000/year in the city of Torino and 8.4 in the non-metropolitan area of the province. These rates are among the highest in Europe. The geographical distribution of cancer of the larynx has been investigated in the non-metropolitan area considering two geographical entities, i.e., the 291 towns and the 12 ecological zones/subzones of the area. The incidence of cancer of the larynx in men was unrelated to the population of towns in 1961, whereas it was positively correlated to indexes of general industrialization as well as to those related to industrialization in the mechanical processes. Tobacco and alcohol consumption have not been taken into account. In order to validate the methodology, the investigation was extended to bladder cancer and to cancer in the children. The former was correlated with general and chemical + rubber industrialization, whereas the latter was not correlated with any industrial process.
1965年至1969年期间，都灵市男性喉癌的年龄标准化发病率为每年14.7/10万，该省非都市地区为8.4/10万。这些发病率在欧洲处于最高水平之列。在非都市地区，考虑到两个地理实体，即该地区的291个城镇和12个生态区/子区域，对喉癌的地理分布进行了调查。1961年男性喉癌发病率与城镇人口无关，而与总体工业化指数以及与机械加工行业工业化相关的指数呈正相关。烟草和酒精消费未纳入考虑范围。为了验证该方法，调查范围扩大到膀胱癌和儿童癌症。前者与总体及化学+橡胶行业的工业化相关，而后者与任何工业过程均无关联。
