Bull World Health Organ. 1971;45(4):451-5.
A controlled field study of the treatment of cholera carriers is described. The households of cholera patients were assigned to two groups: one group received 2 doses of tetracycline daily for 3 days and the other received a placebo of multivitamins. From the second to the fifth day of follow-up, there was a significant decrease in the number of vibrio excretors in the treated group as compared with the placebo group. Soon after withdrawal of the drug, the number of excretors rose in the treated group and ultimately it was the same in both groups.
本文描述了一项关于霍乱带菌者治疗的对照现场研究。霍乱患者的家庭被分为两组:一组每天接受2剂四环素,共3天,另一组接受多种维生素安慰剂。在随访的第二天至第五天,与安慰剂组相比,治疗组的弧菌排泄者数量显著减少。停药后不久,治疗组的排泄者数量上升,最终两组相同。