强力霉素治疗霍乱
Doxycycline in the treatment of cholera.
作者信息
De S, Chaudhuri A, Dutta P, Dutta D, De S P, Pal S C
出版信息
Bull World Health Organ. 1976;54(2):177-9.
Doxycycline was compared with tetracycline in the treatment of cholera. Four types of treatment were compared: Group A was given 200 mg of doxycycline on admission and 100 mg on the second day; Group B was given 200 mg of doxycycline on admission only; Group C was given 300 mg of doxycycline on admission only; and Group D received 500 mg of tetracycline every 6 h for 48 h. Tetracycline showed a slight advantage in respect of duration of diarrhoea and vibrio excretion compared with doxycycline given as a single dose of 300 mg, but fluid intake and output were about the same in these two groups. The other two doxycycline treatment schedules did not compare well with tetracycline treatment.
在霍乱治疗中，对多西环素和四环素进行了比较。比较了四种治疗方式：A组在入院时给予200毫克多西环素，第二天给予100毫克；B组仅在入院时给予200毫克多西环素；C组仅在入院时给予300毫克多西环素；D组每6小时给予500毫克四环素，持续48小时。与单次给予300毫克多西环素相比，四环素在腹泻持续时间和弧菌排泄方面显示出轻微优势，但这两组的液体摄入量和排出量大致相同。多西环素的其他两种治疗方案与四环素治疗相比效果不佳。
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