Pollák Z, Fodor J, Erdélyi V, Bihari O, Eckhardt S
Acta Radiol Oncol Radiat Phys Biol. 1979;18(2):97-102. doi: 10.3109/02841867909128195.
Patients with basal cell carcinoma of the skin were treated with combined MTDQ (6,6'-methylene-bis-(2,2,4-trimethyl-1,2-dihydroquinoline)) administration and irradiation. Significantly better results were obtained with a skin exposure of 2 000 R combined with MTDQ than with the same dose alone. The results were comparable to those obtained with an exposure of 4 000 R. MTDQ administration induced decrease of tissular malonaldehyde concentration and suggested the peroxide-decomposing action of the radiation sensitizer.
皮肤基底细胞癌患者接受了MTDQ（6,6'-亚甲基-双-(2,2,4-三甲基-1,2-二氢喹啉)）联合照射治疗。2000伦琴皮肤照射联合MTDQ治疗取得的效果明显优于单纯相同剂量照射。其结果与4000伦琴照射取得的结果相当。给予MTDQ可使组织丙二醛浓度降低，提示该辐射增敏剂具有过氧化物分解作用。
