Aguzzi G, Woolf C R, Paterson J F
Can Med Assoc J. 1966 Apr 30;94(18):932-9.
One hundred men and 100 women between the ages of 70 and 89 years were examined clinically and with pulmonary function tests to determine the prevalence and type of chronic obstructive bronchopulmonary disease in very old people. Rhonchi were present in 45% of the old men and 24% of the old women. Obstruction to air flow (FEV(1) < 60% of FVC) was demonstrated in 23% of the men and 6% of the women. Chronic bronchitis was present in 32% and 12% of the old men and women, respectively. Only five individuals, all men, showed emphysema as defined by significant obstruction to air flow with a low diffusing capacity. In old people there was a relationship between smoking, chronic cough and obstruction to air flow.
对100名年龄在70至89岁之间的男性和100名同龄女性进行了临床检查和肺功能测试,以确定高龄人群中慢性阻塞性支气管肺疾病的患病率和类型。45%的老年男性和24%的老年女性存在干啰音。23%的男性和6%的女性存在气流受限(第一秒用力呼气容积<用力肺活量的60%)。老年男性和女性中慢性支气管炎的患病率分别为32%和12%。只有5名个体(均为男性)表现出符合气流显著受限且弥散能力降低定义的肺气肿。在老年人中,吸烟、慢性咳嗽和气流受限之间存在关联。