Solleveld H A
Acta Zool Pathol Antverp. 1979 Jun(72):5-18.
In addition to studies in man, animal models may serve as important tools in the detection of the etiology, biology and treatment of certain types of human cancers. Various models have become available by performing life span studies on 2 rat strains, viz WAG/Rij, BN/Bi and (WAG x BN) F1 hybrid and on Praomys natalensis. Several of these models are described. A basic prerequisite for these types of studies is the availability of animals of good quality. After a general description of the quality of laboratory animals the desirable health status of animals in cancer research is discussed.
除了人体研究外，动物模型可作为检测某些类型人类癌症的病因、生物学特性及治疗方法的重要工具。通过对两种大鼠品系即WAG/Rij、BN/Bi和（WAG×BN）F1杂种以及对南非原鼠进行寿命研究，已获得了各种模型。本文描述了其中几种模型。这类研究的一个基本前提是要有高质量的动物。在对实验动物的质量作了一般性描述之后，本文讨论了癌症研究中实验动物理想的健康状况。
