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恒河猴对体内感受性刺激的操作性辨别

Operant discrimination of an interoceptive stimulus in rhesus monkeys.

作者信息

Slucki H, Adam G, Porter R W

出版信息

J Exp Anal Behav. 1965 Nov;8(6):405-14. doi: 10.1901/jeab.1965.8-405.

DOI:10.1901/jeab.1965.8-405
PMID:4954822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1338122/
Abstract

Five rhesus macaques monkeys surgically prepared with Thiry small intestinal (jejunum) loops and implanted brain electrodes were restrained in primate chairs and kept on 23-hr deprivation-feeding cycle. After being trained to press a lever for sugar pills on an FR 25 schedule of reinforcement, a discrimination training procedure was established. Lever presses were reinforced during the S(D)-a non-aversive mechanical stimulus applied to the internal walls of the Thiry loop by rhythmic inflation-deflation of a small latex balloon by air at the rate of one cycle per sec at 100 mm Hg pressure. The S(Delta) was the absence of the visceral stimulation. The monkeys successfully discriminated between presence and absence of the internal stimulus. A discrimination reversal was attempted and completed on one monkey. The results clearly show operant discrimination based on an interoceptive stimulus. Cortical and subcortical EEG records reflected the onset but not termination of the visceral stimulation.

摘要

五只恒河猴通过手术制备了30个小肠(空肠)肠袢,并植入了脑电极,被限制在灵长类动物椅上,维持23小时禁食-喂食周期。在按照固定比率25强化程序训练它们按压杠杆以获取糖丸后,建立了辨别训练程序。在S(D)期间,杠杆按压得到强化——通过一个小乳胶气球以每秒一个周期、100毫米汞柱的压力有节奏地充气-放气,对30号肠袢内壁施加一种无厌恶感的机械刺激。S(Δ)是没有内脏刺激。猴子成功地区分了内部刺激的存在与否。对一只猴子尝试并完成了辨别反转。结果清楚地表明基于内感受性刺激的操作性辨别。皮层和皮层下脑电图记录反映了内脏刺激的开始,但没有反映其终止。

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