3-甲基巯基-N-甲基-4-氨基偶氮苯：在喂食N，N-二甲基-4-氨基偶氮苯的大鼠肝脏中，一种与蛋白质结合的不稳定染料的碱性降解产物。 - Suppr

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超能文献

3-methylmercapto-N-methyl-4-aminoazobenzene: an alkaline-degradation product of a labile protein-bound dye in the livers of rats fed N,N-dimethyl-4-aminoazobenzene.

作者信息

Scribner J D, Miller J A, Miller E C

出版信息

Biochem Biophys Res Commun. 1965 Sep 8;20(5):560-5. doi: 10.1016/0006-291x(65)90435-3.

DOI:10.1016/0006-291x(65)90435-3

PMID:4955463

Abstract

摘要

相似文献

3-methylmercapto-N-methyl-4-aminoazobenzene: an alkaline-degradation product of a labile protein-bound dye in the livers of rats fed N,N-dimethyl-4-aminoazobenzene.3-甲基巯基-N-甲基-4-氨基偶氮苯：在喂食N，N-二甲基-4-氨基偶氮苯的大鼠肝脏中，一种与蛋白质结合的不稳定染料的碱性降解产物。

Biochem Biophys Res Commun. 1965 Sep 8;20(5):560-5. doi: 10.1016/0006-291x(65)90435-3.

The carcinogenicity of certain derivatives of p-dimethylaminozobenz in the rat.对二甲氨基偶氮苯某些衍生物在大鼠体内的致癌性。

J Exp Med. 1948 Feb 1;87(2):139-56. doi: 10.1084/jem.87.2.139.

Mutagenicity of carcinogenic azo dyes and their derivatives.

Cancer Lett. 1975 Nov;1(2):91-6. doi: 10.1016/s0304-3835(75)95563-9.

Formation of N-(glutathion-S-methylene)-4-aminoazobenzene following metabolic oxidation of the N-methyl group of the carcinogen, N-methyl-4-aminoazobenzene.致癌物N-甲基-4-氨基偶氮苯的N-甲基经代谢氧化后形成N-（谷胱甘肽-S-亚甲基）-4-氨基偶氮苯。

Chem Biol Interact. 1982 Feb;38(3):287-302. doi: 10.1016/0009-2797(82)90059-x.

Sulfuric acid esters as major ultimate electrophilic and hepatocarcinogenic metabolites of 4-aminoazobenzene and its N-methyl derivatives in infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice.硫酸酯作为4-氨基偶氮苯及其N-甲基衍生物在雄性幼龄C57BL/6J×C3H/HeJ F1（B6C3F1）小鼠体内的主要最终亲电及致癌代谢产物。

Carcinogenesis. 1986 Feb;7(2):277-87. doi: 10.1093/carcin/7.2.277.

4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice.4-氨基偶氮苯和N,N-二甲基-4-氨基偶氮苯作为雄性C57BL/6×C3H/He F1小鼠中具有同等效力的肝致癌物以及N-(脱氧鸟苷-8-基)-4-氨基偶氮苯作为这些小鼠肝脏中主要持久性DNA结合染料的特性

Cancer Res. 1984 Jun;44(6):2540-50.

Studies on the intracellular composition of livers from rats fed various aminoazo dyes; 4-aminoazobenzene, 4-dimethylaminoazobenzene, 4'-methyl-, and 3'-methyl-4-dimethyl-aminoazobenzen.对喂食各种氨基偶氮染料（4-氨基偶氮苯、4-二甲基氨基偶氮苯、4'-甲基-和3'-甲基-4-二甲基氨基偶氮苯）的大鼠肝脏细胞内成分的研究。

Cancer Res. 1949 Jul;9(7):398-402.

Hepatic metabolism of N-hydroxy-N-methyl-4-aminoazobenzene and other N-hydroxy arylamines to reactive sulfuric acid esters.N-羟基-N-甲基-4-氨基偶氮苯及其他N-羟基芳胺在肝脏中代谢为活性硫酸酯。

Cancer Res. 1976 Jul;36(7 PT 1):2350-9.

Microsomal N-oxidation of the hepatocarcinogen N-methyl-4-aminoazobenzene and the reactivity of N-hydroxy-N-methyl-4-aminoazobenzene.

Cancer Res. 1976 Mar;36(3):1196-1206.

Detection by antihapten antibodies of liver-bound compounds related to azocarcinogens or their metabolites.通过抗半抗原抗体检测与偶氮致癌物或其代谢产物相关的肝结合化合物。

Oncology. 1979;36(5):211-5. doi: 10.1159/000225344.

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Filling and mining the reactive metabolite target protein database.填充和挖掘反应性代谢物靶蛋白数据库。

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Some historical aspects of N-aryl carcinogens and their metabolic activation.N-芳基致癌物及其代谢活化的一些历史方面

Environ Health Perspect. 1983 Mar;49:3-12. doi: 10.1289/ehp.83493.

Biochemical patterns in brain tumours. 3. Transfer ribonucleic acid.脑肿瘤中的生化模式。3. 转移核糖核酸

Acta Neurochir (Wien). 1969;21(2):123-37. doi: 10.1007/BF01540920.

Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.大鼠体内二甲基亚硝胺和蛋氨酸对核蛋白的甲基化作用。

Biochem J. 1971 Oct;124(4):725-39. doi: 10.1042/bj1240725.

[The activation of carcinogenic aromatic amines in metabolism].[致癌性芳香胺在代谢中的活化作用]

Klin Wochenschr. 1970 Aug 15;48(16):959-66. doi: 10.1007/BF01484398.

Identification of the amino acid residues that bind azo-dye in the soluble azo-dye carcinogen-binding proteins of rat liver.大鼠肝脏可溶性偶氮染料致癌物结合蛋白中与偶氮染料结合的氨基酸残基的鉴定。

Biochem J. 1968 Sep;109(3):37P. doi: 10.1042/bj1090037pa.

The isolation of carcinogen-binding protein from livers of rats given 4-dimethylaminoazobenzene.从给予4-二甲基氨基偶氮苯的大鼠肝脏中分离致癌物结合蛋白。

Biochem J. 1967 May;103(2):316-24. doi: 10.1042/bj1030316.

[On the biological formation of N,N-dimethylanilin-N-oxide and N,N-dimethylaminoazobenzol-N4-oxide from amines as well as their reactions with hemoglobin and liver microsomes].[关于由胺类生物合成N，N-二甲基苯胺-N-氧化物和N，N-二甲基氨基偶氮苯-N4-氧化物及其与血红蛋白和肝微粒体的反应]

Naunyn Schmiedebergs Arch Pharmakol Exp Pathol. 1966;255(3):287-300.

Mechanism of biosynthesis of methylsulfones from PCBs and related compounds.多氯联苯及相关化合物合成甲基砜的机制。

Environ Health Perspect. 1985 Feb;59:129-35. doi: 10.1289/ehp.59-1568084.

[Metabolism of 3-amino-1,2,4-triazole in rats].[大鼠体内3-氨基-1,2,4-三唑的代谢]

Arch Toxicol. 1975 Dec 18;34(4):315-24. doi: 10.1007/BF00353851.

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