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小鼠肠道中的大肠菌群。

Coliform bacteria in the intestine of mice.

作者信息

Mushin R, Dubos R

出版信息

J Exp Med. 1966 Apr 1;123(4):657-63. doi: 10.1084/jem.123.4.657.

DOI:10.1084/jem.123.4.657
PMID:4956528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2180465/
Abstract

Mice of the NCS and NCS-D colonies, bred at the Rockefeller University, harbored in their intestine an endemic strain of slow lactose-fermenting Escherichia coli 081+/-: :H21 serotype. In addition, NCS mice have recently acquired E. coli 0109+/-:K48:H14. Both strains persisted during the period of observation, whereas they were not encountered in the feces of mice from two other colonies. Other coliform strains encountered were more transient in their occurrence. Since strains of E. coli 081+/-: :H21 and 0109+/-:K48:H14 are extremely uncommon in human beings, it seems probable that they possess specificity for the mouse host.

摘要

在洛克菲勒大学培育的NCS和NCS - D群体的小鼠，其肠道中存在一种地方性的缓慢乳糖发酵大肠杆菌081+/-: :H21血清型。此外，NCS小鼠最近又感染了大肠杆菌0109+/-:K48:H14。在观察期间，这两种菌株都持续存在，而在其他两个群体的小鼠粪便中未发现它们。所遇到的其他大肠菌群菌株出现的时间更短暂。由于大肠杆菌081+/-: :H21和0109+/-:K48:H14菌株在人类中极为罕见，它们似乎对小鼠宿主具有特异性。

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本文引用的文献

1
THE EFFECT OF ANTIBACTERIAL DRUGS ON THE WEIGHT OF MICE.抗菌药物对小鼠体重的影响。
J Exp Med. 1963 Jan 31;117(2):245-57. doi: 10.1084/jem.117.2.245.
2
Persistence of individual strains of Escherichia coli in the intestinal tract of man.大肠杆菌个别菌株在人体肠道内的持久性。
J Bacteriol. 1950 Feb;59(2):293-301. doi: 10.1128/jb.59.2.293-301.1950.
3
The fecal flora of various strains of mice. Its bearing on their susceptibility to endotoxin.不同品系小鼠的粪便菌群。其与小鼠对内毒素易感性的关系。
J Exp Med. 1962 Jun 1;115(6):1149-60. doi: 10.1084/jem.115.6.1149.
4
The effect of the intestinal flora on the growth rate of mice, and on their susceptibility to experimental infections.肠道菌群对小鼠生长速率及其对实验性感染易感性的影响。
J Exp Med. 1960 Mar 1;111(3):407-17. doi: 10.1084/jem.111.3.407.
5
Colonization of the mouse intestine with Escherichia coli.用大肠杆菌对小鼠肠道进行定殖。
J Exp Med. 1965 Oct 1;122(4):745-57. doi: 10.1084/jem.122.4.745.

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