Spanos H G, Hecker J F
Anaesth Intensive Care. 1979 Aug;7(3):244-7. doi: 10.1177/0310057X7900700306.
Heparin, aspirin and dipyridamole were given alone or in combination to groups of sheep which had polyethylene catheters inserted into facial and saphenous veins. Animals were killed after 3 or 9 days. Neither aspirin nor dipyridamole reduced the amounts of thrombus on the catheters at autopsy. Heparin reduced thrombus only when sufficient was given to reduce blood coagulation.
将肝素、阿司匹林和双嘧达莫单独或联合给予几组在面部静脉和隐静脉插入聚乙烯导管的绵羊。在3天或9天后处死动物。尸检时，阿司匹林和双嘧达莫均未减少导管上的血栓量。只有给予足够量的肝素以降低血液凝固时，肝素才能减少血栓形成。
