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The metabolic conversion of primidone (Mysoline) to phenobarbitone in patients under long-term treatment. An attempt to estimate the independent effect of primidone.

作者信息

Olesen O V, Dam M

出版信息

Acta Neurol Scand. 1967;43(3):348-56. doi: 10.1111/j.1600-0404.1967.tb05737.x.

DOI:10.1111/j.1600-0404.1967.tb05737.x
PMID:4963518
Abstract
摘要

相似文献

1
The metabolic conversion of primidone (Mysoline) to phenobarbitone in patients under long-term treatment. An attempt to estimate the independent effect of primidone.
Acta Neurol Scand. 1967;43(3):348-56. doi: 10.1111/j.1600-0404.1967.tb05737.x.
2
Metabolic disposition of primidone and its metabolites in epileptic subjects after single and repeated administration.
Neurology. 1972 Nov;22(11):1186-92. doi: 10.1212/wnl.22.11.1186.
3
Variation in response to anticonvulsants in a group of epileptic patients.一组癫痫患者对抗惊厥药反应的差异。
Arch Neurol. 1972 Jul;27(1):29-33. doi: 10.1001/archneur.1972.00490130031004.
4
Phenylethylmalonamide (PEMA). An important metabolite of primidone.
Arch Neurol. 1972 Jul;27(1):34-41. doi: 10.1001/archneur.1972.00490130036005.
5
Drug treatment of epilepsy in childhood.儿童癫痫的药物治疗
Br Med J. 1969 Nov 22;4(5681):475-7. doi: 10.1136/bmj.4.5681.475.
6
[On the combination treatment of epileptic attacks].[论癫痫发作的联合治疗]
Wien Med Wochenschr. 1968 Feb 10;118(6):116-8.
7
Epilepsy.癫痫
Br Med J. 1969 Nov 1;4(5678):281-4. doi: 10.1136/bmj.4.5678.281.
8
[Results of treatment of epilepsy in children up to 14 years of age].[14岁及以下儿童癫痫的治疗结果]
Neurol Neurochir Pol. 1971;5(3):399-402.
9
Valproic acid and plasma levels of primidone and derived phenobarbital.丙戊酸与扑米酮及其代谢产物苯巴比妥的血药浓度
Can J Neurol Sci. 1981 Feb;8(1):91-2. doi: 10.1017/s0317167100042931.
10
[Problems of therapeutic service in primidone therapy].[扑米酮治疗中的治疗服务问题]
Z Arztl Fortbild (Jena). 1980 Aug 1;74(15):692-4.

引用本文的文献

1
The history of barbiturates a century after their clinical introduction.巴比妥类药物临床应用一个世纪后的历史。
Neuropsychiatr Dis Treat. 2005 Dec;1(4):329-43.
2
Blood and cerebrospinal fluid pharmacokinetics of primidone and its primary pharmacologically active metabolites, phenobarbital and phenylethylmalonamide in the rat.扑米酮及其主要药理活性代谢产物苯巴比妥和苯乙基丙二酰胺在大鼠体内的血液和脑脊液药代动力学
Eur J Drug Metab Pharmacokinet. 1999 Jul-Sep;24(3):255-64. doi: 10.1007/BF03190029.
3
The effects of phenytoin on phenobarbitone and primidone metabolism.
苯妥英对苯巴比妥和扑米酮代谢的影响。
J Neurol Neurosurg Psychiatry. 1981 Feb;44(2):148-51. doi: 10.1136/jnnp.44.2.148.
4
Changes in primidone/phenobarbitone ratio during pregnancy and the puerperium.孕期及产褥期扑米酮/苯巴比妥比例的变化。
Clin Pharmacokinet. 1984 May-Jun;9(3):252-60. doi: 10.2165/00003088-198409030-00006.
5
Drug treatment of epilepsy: a review.癫痫的药物治疗：综述
Can Med Assoc J. 1983 Feb 1;128(3):261-70.
6
Primidone intoxication in a child.一名儿童的扑米酮中毒
Arch Dis Child. 1969 Apr;44(234):282-4. doi: 10.1136/adc.44.234.282.
7
Recent progress in epilepsy. Diagnostic procedures and treatment.癫痫的最新进展。诊断程序与治疗。
Calif Med. 1973 Jul;119(1):19-48.
8
Antiepileptic drugs: metabolism in pregnancy.
Clin Pharmacokinet. 1979 Jan-Feb;4(1):53-62. doi: 10.2165/00003088-197904010-00005.