癫痫的药物治疗：综述
Drug treatment of epilepsy: a review.
作者信息
Rosenbloom D, Upton A R
出版信息
Can Med Assoc J. 1983 Feb 1;128(3):261-70.
Abstract
Once a decision to treat epilepsy has been made it is necessary to have a thorough knowledge of the benefits, disadvantages, toxic effects, pharmacokinetics and interactions associated with each anticonvulsant. However, by determining the serum concentration and manipulating it within the therapeutic range it should be possible to find a regimen that adequately controls seizures without introducing unnecessary toxic effects. There are special considerations in choosing anticonvulsants to treat epilepsy in pregnancy, febrile convulsions and status epilepticus.
摘要
一旦做出治疗癫痫的决定，就有必要全面了解每种抗惊厥药物的益处、弊端、毒性作用、药代动力学以及相互作用。然而，通过测定血清浓度并将其控制在治疗范围内，应该能够找到一种既能充分控制癫痫发作又不会产生不必要毒性作用的治疗方案。在选择抗惊厥药物治疗妊娠期间的癫痫、热性惊厥和癫痫持续状态时，有一些特殊的考虑因素。
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Drug treatment of epilepsy: a review.癫痫的药物治疗：综述
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