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糖尿病视网膜病变不同阶段的血液流变学异常。代谢控制及后续疾病的影响。

Hemorrheological abnormalities in different states of diabetic retinopathy. Effect of metabolic control and subsequent diseases.

作者信息

Volger E

出版信息

Bibl Anat. 1979(18):60-6.

PMID:496881
Abstract

The flow properties of blood are abnormal in diabetes. The red cell deformability (RCD) is reduced and depends on the metabolic state, the red cell aggregation (RCA) and plasma viscosity are increased independent of the metabolism. 157 diabetics were studied according the following nosological factors: duration of diabetes, type of therapy, ophthalmoscopic status, metabolic state and general health status. Although a deterioration of the flow properties of blood can be observed in long-term diabetics, in patients receiving antidiabetic drugs or insulin and in cases of pronounced retinopathy, these changes can all be attributed to a higher incidence of insufficiently controlled metabolism and the presence of subsequent diseases. There is some evidence that the rheological changes cannot be neglected considering the development and progression of diabetic microangiopathy.

摘要

糖尿病患者血液的流动特性异常。红细胞变形性(RCD)降低,且取决于代谢状态,红细胞聚集性(RCA)和血浆黏度增加,与代谢无关。根据以下疾病学因素对157名糖尿病患者进行了研究:糖尿病病程、治疗类型、眼底镜检查状况、代谢状态和总体健康状况。虽然在长期糖尿病患者、接受抗糖尿病药物或胰岛素治疗的患者以及有明显视网膜病变的患者中可观察到血液流动特性恶化,但这些变化都可归因于代谢控制不佳的发生率较高以及后续疾病的存在。有证据表明,考虑到糖尿病微血管病变的发生和发展,流变学变化不容忽视。

相似文献

1
Hemorrheological abnormalities in different states of diabetic retinopathy. Effect of metabolic control and subsequent diseases.糖尿病视网膜病变不同阶段的血液流变学异常。代谢控制及后续疾病的影响。
Bibl Anat. 1979(18):60-6.
2
Effect of metabolic control and concomitant diseases upon the rheology of blood in different states of diabetic retinopathy.
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Red-cell aggregation and red-cell deformability in diabetes.糖尿病中的红细胞聚集与红细胞变形性
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[Blood viscosity and erythrocyte deformability in diabetic retinopathy].[糖尿病视网膜病变中的血液粘度和红细胞变形性]
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Diabetes mellitus: its effect on the flow properties of blood.糖尿病:其对血液流动特性的影响。
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Reducing lipid peroxidation stress of erythrocyte membrane by alpha-tocopherol nicotinate plays an important role in improving blood rheological properties in type 2 diabetic patients with retinopathy.烟酸生育酚酯降低红细胞膜脂质过氧化应激对改善2型糖尿病视网膜病变患者血液流变学特性具有重要作用。
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