枯草芽孢杆菌中组氨酸和芳香族氨基酸生物合成酶的阻遏控制中的共同要素。
Common element in the repression control of enzymes of histidine and aromatic amino acid biosynthesis in Bacillus subtilus.
作者信息
Chapman L F, Nester E W
出版信息
J Bacteriol. 1968 Nov;96(5):1658-63. doi: 10.1128/jb.96.5.1658-1663.1968.
Abstract
Single-step mutants of Bacillus subtilis derepressed for enzymes of both aromatic amino acid and histidine biosynthesis were isolated. These mutants occur at a frequency of 10(-6) per cell per generation. All histidine enzymes as well as all enzymes of aromatic acid synthesis which were examined are maximally derepressed. This level cannot be repressed by growth on either histidine or tyrosine. Some of the structural genes which specify the derepressed enzymes are linked to the aromatic cluster; others are unlinked. The significance of these nonrepressible strains is discussed in terms of the mechanism of repression.
摘要
分离出了枯草芽孢杆菌的单步突变体，这些突变体对于芳香族氨基酸和组氨酸生物合成的酶来说是去阻遏的。这些突变体的出现频率为每代每细胞10⁻⁶。所检测的所有组氨酸酶以及所有芳香酸合成酶都被最大程度地去阻遏。在组氨酸或酪氨酸上生长都不能使这种水平受到阻遏。一些编码去阻遏酶的结构基因与芳香族基因簇相连；其他的则不相连。根据阻遏机制讨论了这些不可阻遏菌株的意义。
相似文献
1
Common element in the repression control of enzymes of histidine and aromatic amino acid biosynthesis in Bacillus subtilus.枯草芽孢杆菌中组氨酸和芳香族氨基酸生物合成酶的阻遏控制中的共同要素。
J Bacteriol. 1968 Nov;96(5):1658-63. doi: 10.1128/jb.96.5.1658-1663.1968.
2
Cross pathway regulation: effect of histidine on the synthesis and activity of enzymes of aromatic acid biosynthesis in Bacillus subtilis.交叉途径调控：组氨酸对枯草芽孢杆菌芳香酸生物合成中酶的合成及活性的影响
J Bacteriol. 1968 Nov;96(5):1649-57. doi: 10.1128/jb.96.5.1649-1657.1968.
3
Regulation of enzyme synthesis in the aromatic amino acid pathway of Bacillus subtilus.枯草芽孢杆菌芳香族氨基酸途径中酶合成的调控
J Bacteriol. 1969 Jan;97(1):83-90. doi: 10.1128/jb.97.1.83-90.1969.
4
An enzyme common to histidine and aromatic amino acid biosynthesis in Bacillus subtilis.一种存在于枯草芽孢杆菌中参与组氨酸和芳香族氨基酸生物合成的常见酶。
J Bacteriol. 1976 May;126(2):699-705. doi: 10.1128/jb.126.2.699-705.1976.
5
Gene-enzyme relationships in histidine biosynthesis in Bacillus subtilis.枯草芽孢杆菌组氨酸生物合成中的基因-酶关系
J Bacteriol. 1969 Mar;97(3):1444-8. doi: 10.1128/jb.97.3.1444-1448.1969.
6
Metabolic interlock. The influence of histidine on tryptophan biosynthesis in Bacillus subtilis.代谢互锁。组氨酸对枯草芽孢杆菌色氨酸生物合成的影响。
J Biol Chem. 1970 May 10;245(9):2384-90.
7
Regulated enzymes of aromatic amino acid synthesis: control, isozymic nature, and aggregation in Bacillus subtilis and Bacillus licheniformis.芳香族氨基酸合成的调控酶：枯草芽孢杆菌和地衣芽孢杆菌中的控制、同工酶性质及聚集
J Bacteriol. 1969 Apr;98(1):44-50. doi: 10.1128/jb.98.1.44-50.1969.
8
Cross pathway regulation of tyrosine and histidine synthesis in Bacillus subtilis. Biochemical, genetic, and transfer RNA studies.枯草芽孢杆菌中酪氨酸和组氨酸合成的交叉途径调控。生化、遗传学及转运RNA研究。
Biochim Biophys Acta. 1974 Aug 15;361(1):59-72. doi: 10.1016/0005-2787(74)90209-3.
9
Repression of the histidine operon: effect of the first enzyme on the kinetics of repression.组氨酸操纵子的阻遏：第一种酶对阻遏动力学的影响。
J Bacteriol. 1969 Mar;97(3):1283-90. doi: 10.1128/jb.97.3.1283-1290.1969.
10
Aromatic amino acid biosynthesis: gene-enzyme relationships in Bacillus subtilis.芳香族氨基酸生物合成：枯草芽孢杆菌中的基因-酶关系
J Bacteriol. 1967 Nov;94(5):1706-14. doi: 10.1128/jb.94.5.1706-1714.1967.
引用本文的文献
1
Growth Inhibition in Thiobacillus neapolitanus by Histidine, Methionine, Phenylalanine, and Threonine.组氨酸、蛋氨酸、苯丙氨酸和苏氨酸对那不勒斯硫杆菌的生长抑制作用
J Bacteriol. 1970 Dec;104(3):1145-50. doi: 10.1128/jb.104.3.1145-1150.1970.
2
Genomewide transcriptional changes associated with genetic alterations and nutritional supplementation affecting tryptophan metabolism in Bacillus subtilis.与影响枯草芽孢杆菌色氨酸代谢的基因改变和营养补充相关的全基因组转录变化。
Proc Natl Acad Sci U S A. 2003 May 13;100(10):5682-7. doi: 10.1073/pnas.1031606100. Epub 2003 Apr 28.
3
Histidine-mediated control of tryptophan biosynthetic enzymes in Neurospora crassa.组氨酸对粗糙脉孢菌中色氨酸生物合成酶的调控
J Bacteriol. 1970 Oct;104(1):98-106. doi: 10.1128/jb.104.1.98-106.1970.
4
Gene-enzyme relationships in histidine biosynthesis in Bacillus subtilis.枯草芽孢杆菌组氨酸生物合成中的基因-酶关系
J Bacteriol. 1969 Mar;97(3):1444-8. doi: 10.1128/jb.97.3.1444-1448.1969.
5
Cross pathway regulation: effect of histidine on the synthesis and activity of enzymes of aromatic acid biosynthesis in Bacillus subtilis.交叉途径调控：组氨酸对枯草芽孢杆菌芳香酸生物合成中酶的合成及活性的影响
J Bacteriol. 1968 Nov;96(5):1649-57. doi: 10.1128/jb.96.5.1649-1657.1968.
6
Genetic control of the histidine dissimilatory pathway in Pseudomonas putida.恶臭假单胞菌中组氨酸异化途径的遗传控制
Mol Gen Genet. 1973 Feb 2;120(3):201-10. doi: 10.1007/BF00267152.
7
Cross-pathway regulation: histidine-mediated control of histidine, tryptophan, and arginine biosynthetic enzymes in Neurospora crassa.跨途径调控：粗糙脉孢菌中组氨酸介导的对组氨酸、色氨酸和精氨酸生物合成酶的控制
J Bacteriol. 1974 Sep;119(3):893-98. doi: 10.1128/jb.119.3.893-898.1974.
8
Strains of Bacillus subtilis synthesizing elevated levels of isoleucine-valine biosynthetic enzymes.枯草芽孢杆菌菌株合成异亮氨酸-缬氨酸生物合成酶的水平升高。
Mol Gen Genet. 1974 Mar 14;129(2):87-95. doi: 10.1007/BF00268623.
9
Regulation of histidinol phosphate aminotransferase synthesis by tryptophan in Bacillus subtilis.枯草芽孢杆菌中色氨酸对组氨醇磷酸氨基转移酶合成的调控
J Bacteriol. 1976 Oct;128(1):202-11. doi: 10.1128/jb.128.1.202-211.1976.
10
An enzyme common to histidine and aromatic amino acid biosynthesis in Bacillus subtilis.一种存在于枯草芽孢杆菌中参与组氨酸和芳香族氨基酸生物合成的常见酶。
J Bacteriol. 1976 May;126(2):699-705. doi: 10.1128/jb.126.2.699-705.1976.
本文引用的文献
1
Gene Linkage in DNA Transfer: A Cluster of Genes Concerned with Aromatic Biosynthesis in Bacillus Subtilis.DNA转移中的基因连锁：枯草芽孢杆菌中与芳香族生物合成相关的一组基因
Genetics. 1963 Apr;48(4):529-51. doi: 10.1093/genetics/48.4.529.
2
Mutations of Bacteria from Virus Sensitivity to Virus Resistance.细菌从对病毒敏感到对病毒抗性的突变。
Genetics. 1943 Nov;28(6):491-511. doi: 10.1093/genetics/28.6.491.
3
TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE.脱氧核糖核酸对枯草芽孢杆菌生化缺陷菌株的转化
Proc Natl Acad Sci U S A. 1958 Oct 15;44(10):1072-8. doi: 10.1073/pnas.44.10.1072.
4
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
5
Interference with feedback control of enzyme activity.对酶活性反馈控制的干扰。
Cold Spring Harb Symp Quant Biol. 1961;26:323-9. doi: 10.1101/sqb.1961.026.01.039.
6
ROLE OF VALYL-SRNA SYNTHETASE IN ENZYME REPRESSION.缬氨酰 - 转运核糖核酸合成酶在酶阻遏中的作用。
Proc Natl Acad Sci U S A. 1965 Mar;53(3):539-43. doi: 10.1073/pnas.53.3.539.
7
THE REGULATORY SIGNIFICANCE OF INTERMEDIARY METABOLITES: CONTROL OF AROMATIC ACID BIOSYNTHESIS BY FEEDBACK INHIBITION IN BACILLUS SUBTILIS.中间代谢产物的调节意义：枯草芽孢杆菌中通过反馈抑制对芳香酸生物合成的控制
J Mol Biol. 1965 Jun;12:468-81. doi: 10.1016/s0022-2836(65)80270-4.
8
INCREASED ACTIVITY OF TRYPTOPHAN BIOSYNTHETIC ENZYMES IN HISTIDINE MUTANTS OF NEUROSPORA CRASSA.粗糙脉孢菌组氨酸突变体中色氨酸生物合成酶活性的增加。
J Bacteriol. 1965 Jun;89(6):1472-7. doi: 10.1128/jb.89.6.1472-1477.1965.
9
EFFECT OF ALPHA-METHYLHISTIDINE ON THE CONTROL OF HISTIDINE SYNTHESIS.α-甲基组氨酸对组氨酸合成调控的影响。
J Mol Biol. 1964 Sep;9:670-82. doi: 10.1016/s0022-2836(64)80174-1.
Zotero 插件