对长期存在的类圆线虫病缺乏免疫球蛋白E反应。
Lack of immunoglobulin E response to longstanding strongyloidiasis.
作者信息
Gill G V, Bell D R, Fifield R
出版信息
Clin Exp Immunol. 1979 Aug;37(2):292-4.
Abstract
Patients harbouring worm infections usually have very marked elevations of serum immunoglobulin E (IgE) concentration. However, in a group of twenty ex-Far East prisoners of war with strongyloidiasis only two (10%) had raised levels due to the worm, and these were only moderately elevated. This poor IgE response may be related to the very longstanding nature of the infection (at least 30 years). The patients may have a form of immunological incompetence, or may have become immunologically tolerant to the parasite.
摘要
感染蠕虫的患者通常血清免疫球蛋白E（IgE）浓度会显著升高。然而，在一组20名患有类圆线虫病的前远东战俘中，只有两人（10%）因该蠕虫感染导致IgE水平升高，且只是中度升高。这种IgE反应不佳可能与感染的长期存在性质（至少30年）有关。这些患者可能存在某种形式的免疫功能不全，或者可能已对该寄生虫产生免疫耐受。
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