Hladik W B, Dujovne C A
Eur J Clin Pharmacol. 1979 Jul;15(6):411-5. doi: 10.1007/BF00561740.
One hundred consecutive digitalis serum level determination requests and results were analyzed to evaluate the rational of ordering the test and utilizing the results at his hospital. Sixty-six percent of the reasons given for ordering the test were categorized as "acceptable". As many as 25% of physicians requesting the test considered digitalis levels as "routine" diagnostic tests in a patient taking these drugs. There were 12 levels within the potentially toxic range, 19 below the usual therapeutic range. The physicians modified their therapeutic management in 38 patients as a result of their knowledge of the digitalis level in blood. It is concluded that digitalis level determinations at this hospital are reasonably well utilized and that knowledge of the digitalis levels improve the accuracy of digitalis utilization in at least one third of the patients in whom this test is done.
对连续100份洋地黄血清水平测定申请及结果进行了分析，以评估在该医院进行此项检查及利用检查结果的合理性。申请该项检查的原因中，66%被归类为“可接受”。申请该项检查的医生中，多达25%将服用洋地黄药物患者的洋地黄水平视为“常规”诊断检查。有12个水平处于潜在中毒范围内，19个低于通常治疗范围。由于了解了血液中的洋地黄水平，医生对38例患者的治疗方案进行了调整。得出的结论是，该医院对洋地黄水平测定的利用较为合理，并且了解洋地黄水平至少能提高三分之一接受此项检查患者使用洋地黄的准确性。
