一些芳烃和酮类在水、血液及油中的分配系数
Partition coefficients of some aromatic hydrocarbons and ketones in water, blood and oil.
作者信息
Sato A, Nakajima T
出版信息
Br J Ind Med. 1979 Aug;36(3):231-4. doi: 10.1136/oem.36.3.231.
Abstract
Water/air, blood/air, oil/air, oil/water, and oil/blood partition (or solubility) coefficients of 17 aromatic hydrocarbons and ketones were measured by a newly developed vial-equilibration method, which needs no direct measurements of the concentration either in the liquid or in the air phase, but only the gas chromatographic peak heights of the air in the sample (in which a test material is contained) and reference vessels (containing no test material). It was found that the blood/air partition coefficients for aromatic hydrocarbons are correlated closely with the product of water/air and oil/air partitiion coefficients, whereas those for ketones are almost in the same range as the water/air, irrespective of the oil/air partition coefficients.
摘要
通过一种新开发的小瓶平衡法测量了17种芳烃和酮类的水/空气、血液/空气、油/空气、油/水和油/血液分配（或溶解度）系数。该方法无需直接测量液相或气相中的浓度，只需测量样品（含有测试物质）和参考容器（不含测试物质）中空气的气相色谱峰高。结果发现，芳烃的血液/空气分配系数与水/空气和油/空气分配系数的乘积密切相关，而酮类的血液/空气分配系数几乎与水/空气处于相同范围，与油/空气分配系数无关。
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