来自鸡肝的丙酮酸羧化酶。稳态动力学研究表明其存在“双位点”乒乓机制。 - Suppr

Suppr

超能文献

Pyruvate carboxylase from chicken liver. Steady state kinetic studies indicate a "two-site" ping-pong mechanism.

作者信息

Barden R E, Fung C H, Utter M F, Scrutton M C

出版信息

J Biol Chem. 1972 Feb 25;247(4):1323-33.

PMID:5010071

Abstract

摘要

相似文献

Pyruvate carboxylase from chicken liver. Steady state kinetic studies indicate a "two-site" ping-pong mechanism.来自鸡肝的丙酮酸羧化酶。稳态动力学研究表明其存在“双位点”乒乓机制。

J Biol Chem. 1972 Feb 25;247(4):1323-33.

Rat liver pyruvate carboxylase. II. Kinetic studies of the forward reaction.大鼠肝脏丙酮酸羧化酶。II. 正向反应的动力学研究。

J Biol Chem. 1971 Jun 10;246(11):3579-83.

The biotin-dependent enzymes.生物素依赖性酶。

Adv Enzymol Relat Areas Mol Biol. 1971;35:321-442. doi: 10.1002/9780470122808.ch7.

PYRUVATE CARBOXYLASE. IV. PARTIAL REACTIONS AND THE LOCUS OF ACTIVATION BY ACETYL COENZYME A.丙酮酸羧化酶。IV。部分反应及乙酰辅酶A的激活位点。

J Biol Chem. 1965 Feb;240:574-81.

Rat liver pyruvate carboxylase. 3. Isotopic exchange studies of the first partial reaction.大鼠肝脏丙酮酸羧化酶。3. 第一个部分反应的同位素交换研究。

J Biol Chem. 1971 Jun 10;246(11):3584-90.

Pyruvate carboxylase: inactivation by sulfhydryl-group reagents in the presence of certain inorganic anions, substrates, and modifiers and the effects on the allosteric properties of the enzyme.丙酮酸羧化酶：在某些无机阴离子、底物和调节剂存在的情况下被巯基试剂灭活及其对酶别构性质的影响。

Biochim Biophys Acta. 1972 Jul 13;276(1):297-312. doi: 10.1016/0005-2744(72)90032-0.

Acetyl coenzyme A carboxylase. IV. Biotinyl prosthetic group-independent malonyl coenzyme A decarboxylation and carbosyl transfer: generalization to other biotin enzymes.乙酰辅酶A羧化酶。IV. 不依赖生物素辅基的丙二酰辅酶A脱羧和羰基转移：推广至其他生物素酶

J Biol Chem. 1972 Aug 25;247(16):4952-9.

Possible regulatory factors for pyruvate carboxylase with particular reference to enzyme from chicken liver.丙酮酸羧化酶可能的调节因子，特别涉及鸡肝中的该酶。

Metabolism. 1971 Feb;20(2):168-86. doi: 10.1016/0026-0495(71)90090-4.

Nonlinear enzymatic cycling systems: the exponential cycling system. I. Mathematical models.非线性酶循环系统：指数循环系统。I. 数学模型。

J Biol Chem. 1972 Jun 10;247(11):3558-63.

Tricarboxylic acid activator-induced changes at the active site of acetyl-CoA carboxylase.三羧酸激活剂诱导的乙酰辅酶A羧化酶活性位点的变化。

Vitam Horm. 1970;28:345-63. doi: 10.1016/s0083-6729(08)60902-4.

引用本文的文献

A mechanistic modeling framework reveals the key principles underlying tumor metabolism.一种机械建模框架揭示了肿瘤代谢的关键原理。

PLoS Comput Biol. 2022 Feb 11;18(2):e1009841. doi: 10.1371/journal.pcbi.1009841. eCollection 2022 Feb.

Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis.线粒体底物水平磷酸化作为神经胶质母细胞瘤的能量来源：综述与假说。

ASN Neuro. 2018 Jan-Dec;10:1759091418818261. doi: 10.1177/1759091418818261.

Inhibitors of Pyruvate Carboxylase.丙酮酸羧化酶抑制剂

Open Enzym Inhib J. 2010;3:8-26. doi: 10.2174/1874940201003010008.

My favorite pyruvate carboxylase.我最喜欢的丙酮酸羧化酶。

IUBMB Life. 2010 Jul;62(7):535-8. doi: 10.1002/iub.332.

Kinetic studies on two isoforms of acetyl-CoA carboxylase from maize leaves.玉米叶片中乙酰辅酶A羧化酶两种同工型的动力学研究。

Biochem J. 1996 Sep 15;318 ( Pt 3)(Pt 3):997-1006. doi: 10.1042/bj3180997.

Factors that influence the translocation of the N-carboxybiotin moiety between the two sub-sites of pyruvate carboxylase.影响N-羧基生物素部分在丙酮酸羧化酶两个亚位点之间转移的因素。

Biochem J. 1981 Dec 1;199(3):603-9. doi: 10.1042/bj1990603.

Pig liver pyruvate carboxylase. The reaction pathway for the decarboxylation of oxaloacetate.猪肝丙酮酸羧化酶。草酰乙酸脱羧反应途径。

Biochem J. 1974 May;139(2):321-9. doi: 10.1042/bj1390321.

Pig liver pyruvate carboxylase. The reaction pathway for the carboxylation of pyruvate.猪肝丙酮酸羧化酶。丙酮酸羧化反应途径。

Biochem J. 1974 May;139(2):311-20. doi: 10.1042/bj1390311.

Pig liver pyruvate carboxylase. Purification, properties and cation specificity.猪肝丙酮酸羧化酶。纯化、性质及阳离子特异性。

Biochem J. 1974 May;139(2):297-310. doi: 10.1042/bj1390297.

Control of gluconeogenesis in rat liver cells. Flux control coefficients of the enzymes in the gluconeogenic pathway in the absence and presence of glucagon.大鼠肝细胞中糖异生的调控。在有无胰高血糖素情况下糖异生途径中各酶的通量控制系数。

Biochem J. 1986 Jul 15;237(2):379-89. doi: 10.1042/bj2370379.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验