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鱿鱼轴突中钠离子传导的复导纳

Complex admittance of Na+ conduction in squid axon.

作者信息

Fishman H M, Poussart D, Moore L E

出版信息

J Membr Biol. 1979 Oct 5;50(1):43-63. doi: 10.1007/BF01868787.

DOI:10.1007/BF01868787
PMID:501732
Abstract

The complex admittance, Y(p), of squid axon was measured (4--1000 Hz) during step voltage clamp to obtain linear data on Na+ conduction. Y(p) is used as a spectroscopic tool to identify Na+ and K+ conduction, which dominate Y(p) at low frequencies and can be separated from each other and from the static capacitance. Na+ conduction is readily distinguishable from K+ conduction in that it produces a steady-state negative conductance. The admittance of the Na+ system can show an anomalous resonance or an antiresonance depending on whether the net shunt conductance is negative or positive. Use of the Na+ negative conductance to neutralize leakage yields a measurement of dielectric capacitance at low frequency. A 90 degrees phase angle suggests that the capacitance is ideal.

摘要

在阶跃电压钳制期间(4 - 1000赫兹)测量了鱿鱼轴突的复导纳Y(p),以获取关于钠离子传导的线性数据。Y(p)被用作一种光谱工具来识别钠离子和钾离子传导,它们在低频时主导Y(p),并且可以相互分离以及与静态电容分离。钠离子传导很容易与钾离子传导区分开来,因为它会产生稳态负电导。钠离子系统的导纳根据净并联电导是负还是正,可表现出反常共振或反共振。利用钠离子负电导来抵消泄漏可得到低频下介电电容的测量值。90度的相位角表明该电容是理想的。

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