Pettit J E, Hoffbrand A V, Seah P P, Fry L
Br Med J. 1972 May 20;2(5811):438-40. doi: 10.1136/bmj.2.5811.438.
Twenty-four patients with dermatitis herpetiformis were investigated for splenic atrophy by splenic scan and clearance of (51)Cr-labelled heat-damaged red blood cells. Eight of them had definite splenic atrophy. The average splenic cross-sectional area of the remaining 16 with normal clearance times was substantially smaller than normal, suggesting some degree of splenic atrophy. No relationship of splenic hypofunction to intestinal biopsy findings, folate status, reticulin antibody, or treatment with a gluten-free diet or dapsone was evident.
对24例疱疹样皮炎患者进行了脾脏扫描及(51)铬标记的热损伤红细胞清除率检查,以研究脾萎缩情况。其中8例有明确的脾萎缩。其余16例清除时间正常,但其平均脾脏横截面积明显小于正常,提示有一定程度的脾萎缩。未发现脾功能减退与肠道活检结果、叶酸状态、网状纤维抗体或无麸质饮食或氨苯砜治疗之间存在明显关联。