Bowring C S, Glass H I, Lewis S M
J Clin Pathol. 1976 Sep;29(9):852-4. doi: 10.1136/jcp.29.9.852.
The rate of uptake in the spleen of heat-damaged red blood cells labelled with 99mTc has been measured by radioisotope scanning in 38 patients. The values obtained for the half-clearance time into the spleen using this method have been compared with the values obtained simultaneously by blood sampling for the rate of loss of radioactivity from the circulation. It was found that the uptake into the spleen was approximately three times faster than the measured rate of loss of radioactivity from the blood. The reasons for this are discussed and it is suggested that the scanning technique is more reliable as a measure of this aspect of splenic function.
通过放射性同位素扫描测量了38例患者脾脏对用99mTc标记的热损伤红细胞的摄取率。使用该方法获得的进入脾脏的半清除时间值，已与同时通过采血获得的循环中放射性损失率值进行了比较。结果发现，脾脏摄取放射性的速度比从血液中测得的放射性损失速度快约三倍。文中讨论了其原因，并提出扫描技术作为脾脏功能这一方面的测量方法更为可靠。
