哺乳动物锌缺乏时RNA聚合酶活性降低。
Decreased RNA polymerase activity in mammalian zinc deficiency.
作者信息
Terhune M W, Sandstead H H
出版信息
Science. 1972 Jul 7;177(4043):68-9. doi: 10.1126/science.177.4043.68.
PMID:5041777
Abstract
The activity of DNA-dependent RNA polymerase has been measured in liver nuclei from suckling rats nursed by zinc-deficient dams, or by controls that were either pair-fed or given free access to the diet. In the zinc-deficient pups, the activity of the enzyme did not increase; it fell after the tenth day of life.
摘要
用锌缺乏母鼠哺育的乳鼠肝脏细胞核中，或用成对喂养或随意进食对照饮食的母鼠哺育的乳鼠肝脏细胞核中，已对依赖DNA的RNA聚合酶活性进行了测定。在锌缺乏的幼鼠中，该酶的活性并未增加；在出生后第十天之后反而下降。
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