Juge O, Meyer J S, Sakai F, Yamaguchi F, Yamamoto M, Shaw T
Stroke. 1979 Jul-Aug;10(4):428-37. doi: 10.1161/01.str.10.4.428.
Validity of regional blood flow (rCBF) measurements recorded over the human posterior fossa after 133Xe inhalation was tested. Recording of counts from both brain stem and cerebellum (BSC) was reproducible and contamination by counts derived from surrounding anatomical structures was low and no greater than that found over hemispheres. BSC values were F1 = 99 +/- 19 ml/100g brain/min, F2 = 17 +/- 4 in reasonable agreement with data reported from experimental animals. BSC flow values showed significant correlation with the state of awareness as judged by clinical and EEG evaluation with lowest F1 values in semicoma and step increases in stupor, non-REM sleep, drowsiness, rest, activation, REM sleep and highest values during focal and generalized epileptic seizures.
对吸入¹³³氙后人体后颅窝区域脑血流量（rCBF）测量值的有效性进行了测试。脑干和小脑（BSC）的计数记录具有可重复性，周围解剖结构产生的计数污染较低，且不高于半球区域。BSC值为F1 = 99 ± 19 ml/100g脑/分钟，F2 = 17 ± 4，与实验动物报告的数据相当吻合。根据临床和脑电图评估，BSC血流值与意识状态显著相关，在半昏迷状态下F1值最低，在昏迷、非快速眼动睡眠、嗜睡、静息、激活、快速眼动睡眠状态下逐步升高，在局灶性和全身性癫痫发作时达到最高值。
